28395-03-1|Benzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-Products Supply

Benzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy- cas no:28395-03-1

Synonyms: Benzoicacid, 3-(butylamino)-4-phenoxy-5-sulfamoyl- (8CI);3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid;3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid;3-n-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid;Bumex;Burinex;Fontego;Fordiuran;Lixil;Lunetoron;PF1593;Ro 10-6338;

Identification

NameBenzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-
CAS28395-03-1
SynonymsBenzoicacid, 3-(butylamino)-4-phenoxy-5-sulfamoyl- (8CI);3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid;3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid;3-n-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid;Bumex;Burinex;Fontego;Fordiuran;Lixil;Lunetoron;PF1593;Ro 10-6338;
EINECS(EC#)249-004-6
Molecular FormulaC₁₇H₂₀N₂O₅S
Molecular Weight364.4161

Chemical Properties

AppearanceCrystalline Solid
refractive index1.612
storage tempKeep tightly closed. Store in a cool dry place.

Safety Data

Safety

Poison by ingestion, subcutaneous, and intravenous routes. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of SO_x and NO_x.
Safety Information of Bumetanide (CAS NO.28395-03-1):
WGK Germany: 3
RTECS: DG4910000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	> 500ug/kg (0.5mg/kg)	BEHAVIORAL: TETANY BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 66, 1972.
dog	LDLo	oral	> 500ug/kg (0.5mg/kg)	KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 66, 1972.
mammal (species unspecified)	LD50	intravenous	6200ug/kg (6.2mg/kg)	?	Journal of Clinical Pharmacology. Vol. 21, Pg. 543, 1981.
mouse	LD50	intramuscular	> 25mg/kg (25mg/kg)	?	Yakkyoku. Pharmacy. Vol. 27, Pg. 1057, 1976.
mouse	LD50	intraperitoneal	519mg/kg (519mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
mouse	LD50	intravenous	> 200mg/kg (200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
mouse	LD50	oral	4624mg/kg (4624mg/kg)	?	Drugs in Japan Vol. 6, Pg. 683, 1982.
mouse	LD50	subcutaneous	1660mg/kg (1660mg/kg)	?	Drugs in Japan Vol. 6, Pg. 683, 1982.
rabbit	LD50	intravenous	70mg/kg (70mg/kg)	?	Postgraduate Medical Journal, Supplement. Vol. 51(Suppl,
rabbit	LD50	oral	350mg/kg (350mg/kg)	?	Postgraduate Medical Journal, Supplement. Vol. 51(Suppl,
rat	LD50	intramuscular	> 5mg/kg (5mg/kg)	?	Yakkyoku. Pharmacy. Vol. 27, Pg. 1057, 1976.
rat	LD50	intraperitoneal	891mg/kg (891mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 775, 1979.
rat	LD50	intravenous	> 200mg/kg (200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
rat	LD50	oral	> 6gm/kg (6000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
rat	LD50	subcutaneous	> 2gm/kg (2000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Hangzhou Rongda Pharm & Chem Co, Ltd.: Tel:0571-28889928; Address: Xinqiao Development Zone, Yuhang, Hangzhou, China

Fine Chem Trading LTD: Tel:+44-079-7062-7591; Address: PO Box 292, Greenford, UB6 9ZL, England

Shanghai Longschem Co.,Ltd: Tel:; Address: Shanghai Jincheng Road 338 6# 1002 Room

Gyma Laboratories Of America, Inc.: Tel:+1-516-933-0900; Address: 135 Cantiague Rock Rd.Westbury, NY 11590

Antibioticos Spa: Tel:+39-02-9523-5700; Address: Strada Rivoltana Km 6/7, Rodano, MI

Levachem Co. Ltd.: Tel:86-25-83247442 / 443 / 445 / 446 / 447; Address: 2112, SuNing Universal Mansion, 188 Guangzhou Road, Nanjing-210024, China

Zhejiang Chempharm Industry & Trading Co., Ltd.: Tel:0086-571-87701568 87701600; Address: 12,lianhuafeng road,yuhuangshan, Hangzhou,China

Baxter International Inc.: Tel:+1-(847)-948-2000; Address: One Baxter Parkway, Deerfield, Illinois 60015-4625,

Inter-Chemical Ltd.: Tel:+86-(755)-82187211, 82192202; Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005,

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

Conier Chem & Pharma Co.,Ltd.: Tel:+86-(23)-62922305; Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,

AOKChem Co., Ltd.: Tel:+86-(21)-50791030 / 68712331; Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,

Benzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy- cas no:28395-03-1

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