28395-03-1|Benzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-Products Supply

Benzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy- cas no:28395-03-1

Synonyms: Benzoicacid, 3-(butylamino)-4-phenoxy-5-sulfamoyl- (8CI);3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid;3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid;3-n-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid;Bumex;Burinex;Fontego;Fordiuran;Lixil;Lunetoron;PF1593;Ro 10-6338;

Identification

NameBenzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-
CAS28395-03-1
SynonymsBenzoicacid, 3-(butylamino)-4-phenoxy-5-sulfamoyl- (8CI);3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid;3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid;3-n-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid;Bumex;Burinex;Fontego;Fordiuran;Lixil;Lunetoron;PF1593;Ro 10-6338;
EINECS(EC#)249-004-6
Molecular FormulaC₁₇H₂₀N₂O₅S
Molecular Weight364.4161

Chemical Properties

AppearanceCrystalline Solid
refractive index1.612
storage tempKeep tightly closed. Store in a cool dry place.

Safety Data

Safety

Poison by ingestion, subcutaneous, and intravenous routes. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of SO_x and NO_x.
Safety Information of Bumetanide (CAS NO.28395-03-1):
WGK Germany: 3
RTECS: DG4910000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	> 500ug/kg (0.5mg/kg)	BEHAVIORAL: TETANY BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 66, 1972.
dog	LDLo	oral	> 500ug/kg (0.5mg/kg)	KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 66, 1972.
mammal (species unspecified)	LD50	intravenous	6200ug/kg (6.2mg/kg)	?	Journal of Clinical Pharmacology. Vol. 21, Pg. 543, 1981.
mouse	LD50	intramuscular	> 25mg/kg (25mg/kg)	?	Yakkyoku. Pharmacy. Vol. 27, Pg. 1057, 1976.
mouse	LD50	intraperitoneal	519mg/kg (519mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
mouse	LD50	intravenous	> 200mg/kg (200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
mouse	LD50	oral	4624mg/kg (4624mg/kg)	?	Drugs in Japan Vol. 6, Pg. 683, 1982.
mouse	LD50	subcutaneous	1660mg/kg (1660mg/kg)	?	Drugs in Japan Vol. 6, Pg. 683, 1982.
rabbit	LD50	intravenous	70mg/kg (70mg/kg)	?	Postgraduate Medical Journal, Supplement. Vol. 51(Suppl,
rabbit	LD50	oral	350mg/kg (350mg/kg)	?	Postgraduate Medical Journal, Supplement. Vol. 51(Suppl,
rat	LD50	intramuscular	> 5mg/kg (5mg/kg)	?	Yakkyoku. Pharmacy. Vol. 27, Pg. 1057, 1976.
rat	LD50	intraperitoneal	891mg/kg (891mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 775, 1979.
rat	LD50	intravenous	> 200mg/kg (200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
rat	LD50	oral	> 6gm/kg (6000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.
rat	LD50	subcutaneous	> 2gm/kg (2000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 614, 1976.

supplier list

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Wuhan H.X.K Fine Chemicals Co.,LTD: Tel:86-27-59721024; Address: No. 139, hanyang Road, hubei city， Hubei Prov. China 434000

Alfa Chem: Tel:+1-(516)-504-0059, 800-375-6869; Address: 2 Harbor Way, Kings Point, New York 11024,

Suzhou Lixin Pharmaceutical Co., Ltd.: Tel:+86-(512)-8816-9888; Address: No. 21, Tangxi Road, Suzhou New District 215151,

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Haihang Industry Co., Ltd.: Tel:+86-(531)-88032799; Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100,

Watson International Ltd.: Tel:+86-(512)-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,

Chemrio International Limited: Tel:+86-(574)-2789-1268, +86-13957895864; Address: Room 611-612 Wante Business Center, No.487 Yangmuqi Road, Hi-tech Park, Ningbo, Zhejiang 315040,

Hangzhou Sage Chemical Co., Ltd.: Tel:86-571-86818502; Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road

AOKChem Co., Ltd.: Tel:+86-(21)-50791030 / 68712331; Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,

Conier Chem & Pharma Co.,Ltd.: Tel:+86-(23)-62922305; Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,

Chemical Formulations, LLC: Tel:; Address:

Beijing Kaida Technology Development Co., Ltd.: Tel:+86-(010)-62993416; Address: Science and Technology Park, Changping, Beijing torch on the 21st Street, Changping, Beijing 102200,

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

Benzoic acid,3-(aminosulfonyl)-5-(butylamino)-4-phenoxy- cas no:28395-03-1

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