1,3,4-Oxadiazol-2(3H)-one,5-(4-pyridinyl)- cas no:2845-82-1

Synonyms: D2-1,3,4-Oxadiazolin-5-one,2-(4-pyridyl)- (6CI,7CI,8CI); 2-(4-Pyridyl)-1,3,4-oxadiazol-5-one;2-(4-Pyridyl)-D2-1,3,4-oxadiazolin-5-one;5-(4-Pyridyl)-1,3,4-oxadiazol-2-ol; NSC 225247; Neovadrine; S 57

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

Name1,3,4-Oxadiazol-2(3H)-one,5-(4-pyridinyl)-
CAS2845-82-1
SynonymsD2-1,3,4-Oxadiazolin-5-one,2-(4-pyridyl)- (6CI,7CI,8CI); 2-(4-Pyridyl)-1,3,4-oxadiazol-5-one;2-(4-Pyridyl)-D2-1,3,4-oxadiazolin-5-one;5-(4-Pyridyl)-1,3,4-oxadiazol-2-ol; NSC 225247; Neovadrine; S 57
Molecular FormulaC7H5 N3 O2
Molecular Weight175.16

Chemical Properties

refractive index1.702

Safety Data

Safety

Poison by subcutaneous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	700mg/kg (700mg/kg)	BEHAVIORAL: EUPHORIA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 22, 1962.
guinea pig	LD50	subcutaneous	750mg/kg (750mg/kg)	BEHAVIORAL: EUPHORIA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 22, 1962.
mouse	LDLo	oral	2gm/kg (2000mg/kg)	BEHAVIORAL: EUPHORIA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 22, 1962.
mouse	LDLo	subcutaneous	2500mg/kg (2500mg/kg)	BEHAVIORAL: EUPHORIA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 22, 1962.
rabbit	LD50	oral	1gm/kg (1000mg/kg)	BEHAVIORAL: EUPHORIA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 22, 1962.
rabbit	LD50	subcutaneous	400mg/kg (400mg/kg)	BEHAVIORAL: EUPHORIA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 22, 1962.

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