28657-80-9|[1,3]Dioxolo[4,5-g]cinnoline-3-carboxylicacid, 1-ethyl-1,4-dihydro-4-oxo-Products Supply

[1,3]Dioxolo[4,5-g]cinnoline-3-carboxylicacid, 1-ethyl-1,4-dihydro-4-oxo- cas no:28657-80-9

Synonyms: 1-Ethyl-3-carboxy-6,7-methylenedioxy-4-cinnolone;Cinobac; Cinobactin; Cinoxacin; Compound 64716; NSC 304467; Noxigram; Uronorm

Identification

Name[1,3]Dioxolo[4,5-g]cinnoline-3-carboxylicacid, 1-ethyl-1,4-dihydro-4-oxo-
CAS28657-80-9
Synonyms1-Ethyl-3-carboxy-6,7-methylenedioxy-4-cinnolone;Cinobac; Cinobactin; Cinoxacin; Compound 64716; NSC 304467; Noxigram; Uronorm
EINECS(EC#)249-133-8
Molecular FormulaC12H10 N2 O5
Molecular Weight262.22

Chemical Properties

refractive index1.708

Safety Data

Safety

Moderately toxic by ingestion, subcutaneous and intravenous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	850mg/kg (850mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 28(Suppl,
mouse	LD50	oral	2330mg/kg (2330mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 28(Suppl,
mouse	LD50	subcutaneous	900mg/kg (900mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Chemotherapy Vol. 28(Suppl,
rat	LD50	intravenous	860mg/kg (860mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 28(Suppl,
rat	LD50	oral	3610mg/kg (3610mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 28(Suppl,
rat	LD50	subcutaneous	1380mg/kg (1380mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 28(Suppl,

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[1,3]Dioxolo[4,5-g]cinnoline-3-carboxylicacid, 1-ethyl-1,4-dihydro-4-oxo- cas no:28657-80-9

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