3-Chlorophenyl isocyanate cas no:2909-38-8
Synonyms: Benzene, 1-chloro-3-isocyanato-; 1-chloro-3-isocyanato-benzen; 3-Chloroisocyanatobenzene; 3-chlorophenylcarbonimide; benzene,1-chloro-3-isocyanato-; Isocyanic acid, m-chlorophenyl ester; isocyanicacid,m-chlorophenylester; m-Chlorfenylisokyanat; m-chlorophenylcarbonimide; 1-Chloro-3-isocyanato-benzene
Name3-Chlorophenyl isocyanate
CAS2909-38-8
SynonymsBenzene, 1-chloro-3-isocyanato-; 1-chloro-3-isocyanato-benzen; 3-Chloroisocyanatobenzene; 3-chlorophenylcarbonimide; benzene,1-chloro-3-isocyanato-; Isocyanic acid, m-chlorophenyl ester; isocyanicacid,m-chlorophenylester; m-Chlorfenylisokyanat; m-chlorophenylcarbonimide; 1-Chloro-3-isocyanato-benzene
EINECS(EC#)220-822-5
Molecular FormulaC7H4ClNO
Molecular Weight153.57
Appearancecolorless limpid liquid
refractive index1.5576-1.5596
storage tempKeep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Sensitive Moisture Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Hazard T+:Verytoxic;
Risk R26;R36/37/38;R42
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NQ8560000
- CHEMICAL NAME :
- Isocyanic acid, m-chlorophenyl ester
- CAS REGISTRY NUMBER :
- 2909-38-8
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C7-H4-Cl-N-O
- MOLECULAR WEIGHT :
- 153.57
- WISWESSER LINE NOTATION :
- OCNR CG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - other changes
Gastrointestinal - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0528438
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 42 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0530488
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0538092
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 37 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0538092
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 7940 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - other changes
Gastrointestinal - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0528438
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 63 mg/m3
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 11(4),23,1967
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 ug/m3/24H/80D-C
- TOXIC EFFECTS :
- Liver - other changes
Kidney, Ureter, Bladder - other changes in urine composition
Endocrine - other changes
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 32(10),103,1967
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 ug/m3/24H/11W-C
- TOXIC EFFECTS :
- Liver - other changes
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Metabolism (Intermediary) - other proteins
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 32(7),3,1967
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-HUNGARY:STEL 0.05 mg/m3 JAN 1993
OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993
