29122-68-7|Benzeneacetamide,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-Products Supply

Benzeneacetamide,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- cas no:29122-68-7

Synonyms: Acetamide,2-[p-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]- (8CI);(RS)-Atenolol;Alinor;Altol;Anselol;Antipressan;Apo-Atenolol;AteHexal;Atecard;Atelol;Atenblock;Atendol;Atenet;Ateni;Ateno;Atenolol;Aterol;B-Vasc;Betacard;Tenormin;Tenormine;Tensimin;Tredol;Urosin;Vericordin;Xaten;1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol;Catenol;Catenolol;Corotenol;Farnormin;Hipres;ICI 66082;Internolol;Lo-ten;Lotenal;Normalol;Noten;Oraday;Prenormine;SelesBeta;Serten;Telol;Teno-basan;Tenolin;Tenoprin;

Identification

NameBenzeneacetamide,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
CAS29122-68-7
SynonymsAcetamide,2-[p-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]- (8CI);(RS)-Atenolol;Alinor;Altol;Anselol;Antipressan;Apo-Atenolol;AteHexal;Atecard;Atelol;Atenblock;Atendol;Atenet;Ateni;Ateno;Atenolol;Aterol;B-Vasc;Betacard;Tenormin;Tenormine;Tensimin;Tredol;Urosin;Vericordin;Xaten;1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol;Catenol;Catenolol;Corotenol;Farnormin;Hipres;ICI 66082;Internolol;Lo-ten;Lotenal;Normalol;Noten;Oraday;Prenormine;SelesBeta;Serten;Telol;Teno-basan;Tenolin;Tenoprin;
EINECS(EC#)249-451-7
Molecular FormulaC₁₄H₂₂N₂O₃
Molecular Weight266.34

Chemical Properties

AppearanceWhite to off-white crystalline powder
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Hazard UN NO.
Risk R22
Safety

Safety Information of?Atenolol (CAS NO.29122-68-7):
Hazard Codes: Xn
Risk Statements: 22-36/37/38-20/21/22
22: Harmful if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements: 22-24/25-36-26
22: Do not breathe dust
24/25: Avoid contact with skin and eyes
36: Wear suitable protective clothing
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany: 2
RTECS: AC3600000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	10204ug/kg (10.204mg/kg)	BEHAVIORAL: COMA CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Anesthesiology. Vol. 83, Pg. 204, 1995.
man	TDLo	oral	49mg/kg/30D-I (49mg/kg)	BEHAVIORAL: EXCITEMENT	Journal of Clinical Pyschopharmacology. Vol. 6, Pg. 390, 1986.
man	TDLo	oral	86mg/kg/60D-I (86mg/kg)	BLOOD: "CHANGES IN SERUM COMPOSITION (E.G., TP, BILIRUBIN, CHOLESTEROL)"	American Journal of Medicine. Vol. 85, Pg. 586, 1988.
man	TDLo	oral	129mg/kg/26W- (129mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: COUGH LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Annales de Medecine Interne. Vol. 148, Pg. 505, 1997.
mouse	LD50	intraperitoneal	134mg/kg (134mg/kg)	?	Toksikologicheskii Vestnik. Vol. (4), Pg. 33, 1995.
mouse	LD50	intravenous	57mg/kg (57mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4579, 1980.
mouse	LD50	oral	2gm/kg (2000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4579, 1980.
mouse	LD50	subcutaneous	> 400mg/kg (400mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4579, 1980.
rabbit	LD50	intravenous	50mg/kg (50mg/kg)	?	Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. Vol. 17, Pg. 425, 1979.
rat	LD50	intravenous	77mg/kg (77mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4579, 1980.
rat	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4579, 1980.
rat	LD50	subcutaneous	> 600mg/kg (600mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4579, 1980.
women	TDLo	oral	16mg/kg (16mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION	Annals of Emergency Medicine. Vol. 14, Pg. 161, 1985.
women	TDLo	oral	42mg/kg/3W-I (42mg/kg)	?	British Medical Journal. Vol. 294, Pg. 1324, 1987.
women	TDLo	oral	1080mg/kg/78W (1080mg/kg)	BLOOD: LEUKOPENIA MUSCULOSKELETAL: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Journal of Rheumatology. Vol. 13, Pg. 446, 1986.

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Benzeneacetamide,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- cas no:29122-68-7

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