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Home > products > 2H-[1]Benzothieno[2,3-e]-1,4-diazepin-2-one,1,3,6,7,8,9-hexahydro-5-phenyl-

2H-[1]Benzothieno[2,3-e]-1,4-diazepin-2-one,1,3,6,7,8,9-hexahydro-5-phenyl- cas no:29462-18-8

Synonyms: Bentazepam;CI 718; QM 6008; Thiadipone; Tiadipone

Identification
Name2H-[1]Benzothieno[2,3-e]-1,4-diazepin-2-one,1,3,6,7,8,9-hexahydro-5-phenyl-
CAS29462-18-8
SynonymsBentazepam;CI 718; QM 6008; Thiadipone; Tiadipone
Molecular FormulaC17H16 N2 O S
Molecular Weight296.41
Chemical Properties
refractive index1.733
Safety Data

Safety

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SOx and NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 129mg/kg/17W- (129mg/kg) BEHAVIORAL: ANOREXIA (HUMAN

BEHAVIORAL: MUSCLE WEAKNESS

LIVER: LIVER FUNCTION TESTS IMPAIRED
Lancet. Vol. 343, Pg. 860, 1994.
mouse LD50 intraperitoneal 630mg/kg (630mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 926, 1975.
mouse LD50 oral 980mg/kg (980mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 926, 1975.
rat LD50 oral 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 926, 1975.
women TDLo oral 84mg/kg/8W-I (84mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Journal of Clinical Gastroenterology. Vol. 25, Pg. 710, 1997.

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