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Piperazine,1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)- cas no:298-57-7

Synonyms: Piperazine,1-cinnamyl-4-(diphenylmethyl)- (6CI,7CI,8CI);1-(3-Phenylallyl)-4-(diphenylmethyl)piperazine;1-Cinnamyl-4-(diphenylmethyl)piperazine;1-Diphenylmethyl-4-cinnamoylpiperazine;516MD;Aplactan;Apotomin;Carecin;Cerepar;Cinarizine;Cinnacet;Cinnipirine;Denapol;Dimitronal;Folcodal;Glanil;Ixterol;Labyrin;Marisan;Mitronal;Olamin;Sepan;Spaderizine;Stutgeron;Toliman;

Identification
NamePiperazine,1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)-
CAS298-57-7
SynonymsPiperazine,1-cinnamyl-4-(diphenylmethyl)- (6CI,7CI,8CI);1-(3-Phenylallyl)-4-(diphenylmethyl)piperazine;1-Cinnamyl-4-(diphenylmethyl)piperazine;1-Diphenylmethyl-4-cinnamoylpiperazine;516MD;Aplactan;Apotomin;Carecin;Cerepar;Cinarizine;Cinnacet;Cinnipirine;Denapol;Dimitronal;Folcodal;Glanil;Ixterol;Labyrin;Marisan;Mitronal;Olamin;Sepan;Spaderizine;Stutgeron;Toliman;
EINECS(EC#)206-064-8
Molecular FormulaC26H28N2
Molecular Weight368.56
Chemical Properties
Appearancewhite powder
refractive index1.649
storage tempRefrigerator
Safety Data

Hazard Xn
Risk R20/22
Safety

Poison by intravenous route. Moderately toxic by intraperitoneal route. Experimental reproductive effects. Human systemic effects by ingestion: allergic dermatitis. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:Xn
Risk Statements:
20: ?Harmful by inhalation?
22: ?Harmful if swallowed?
36: ?Irritating to the eyes
37: ?Irritating to the respiratory system
38: ?Irritating to the skin
42: ?May cause sensitization by inhalation
43: ?May cause sensitization by skin contact?
Safety Statements:
22: ?Do not breathe dust
24: ?Avoid contact with skin
25: ?Avoid contact with eyes
26: ?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36: ?Wear suitable protective clothing


Toxicity
1. ???

orl-wmn TDLo:252?mg/kg/12W-I:SKN

??? BJDEAZ ?? British Journal of Dermatology. 112 (1985),607.
2. ???

ipr-rat LD50:1050?mg/kg

??? MDACAP ?? Medicamentos de Actualidad. 21 (1985),443.
3. ???

ivn-rat LD50:24?mg/kg

??? KSRNAM ?? Kiso to Rinsho. Clinical Report. 16 (1982),1735.
4. ???

ipr-mus LD50:730?mg/kg

??? MDACAP ?? Medicamentos de Actualidad. 21 (1985),443.
5. ???

ivn-mus LD50:22?mg/kg

??? KSRNAM ?? Kiso to Rinsho. Clinical Report. 16 (1982),1735.

supplier list

Saniver Limited
Tel:
Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.
Tianjin Harmony Technology Development Co., Ltd.
Tel:
Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
INFA S.P.A.
Tel:+39-02-777281
Address: Via Salvini 10, 20122 Milan (Italy)
grandachem Ltd.
Tel:
Address: 11F, No.Hubin North Road,Siming Area, Xiamen China.
Hangzhou Starshine Pharmaceutical Co., LTD
Tel:86-571-8696517
Address: Fengqi East Road, Hangzhou, China.
Zhejiang Yulong Chemical Co.,Ltd.
Tel:
Address: NO.165 ZHONGHE ZHONG ROAD, HANGZHOU, CHINA.
Transo-Pharm
Tel:+49 4107 8779 333
Address: B榛畉bek 5 22962 Siek Germany
D Maniar and Brothers
Tel:+91-22-26105345锛?6105355
Address: 10, Shaniya Enclave, 5th FloorVallabhai RoadNear Railway Crossing Vile Parle (West) Mumbai - 400 056 INDIA.
NORBRIGHT INDUTRY CO., LTD
Tel:
Address: E7602+03, BINHAI JINRONGJIE, 20 GUANGCHANGDONG ROAD,TEDA, TIANJIN 300457 CHINA
THYKN (INDIA) INTERNATIONAL
Tel:+91-22-67033666 (3 lines)
Address: 202, Kuntal, Mody Estate, Nr.Pipeline, LBS Road, Ghatkopar (West), Mumbai - 400086, India
BU of APIs of Shanghai Pharmaceutical(Group)Co.,L...
Tel:
Address: 200,Taicang Road,Shanghai P.R.China
Hikal Ltd.
Tel:+91-22-27574276
Address: 603A, Great Eastern Chambers, Sector 11, CBD-Belapur , Navi Mumbai - 400 614. India
Fleming Laboratories Limited
Tel:+91 40 2781 6714 / 27848791 / 27845697
Address: Plot #: 48 Temple Rock Enclave Tarbund 'X' Roads Secunderabad 500 009 Andhra Pradesh, India
La Nova Chem
Tel:+91-22-5692-1530/31/32
Address: E-404, Remi Biz Court,Veera Desai Road, Andheri (West),Mumbai - 400058, India.
Healthy Life Pharma (P) Limited
Tel:+91-22-32403692/32459914
Address: 401, Richa, B-29, New Andheri Link Road, Andheri (W)

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