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Piperazine,1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)- cas no:298-57-7

Synonyms: Piperazine,1-cinnamyl-4-(diphenylmethyl)- (6CI,7CI,8CI);1-(3-Phenylallyl)-4-(diphenylmethyl)piperazine;1-Cinnamyl-4-(diphenylmethyl)piperazine;1-Diphenylmethyl-4-cinnamoylpiperazine;516MD;Aplactan;Apotomin;Carecin;Cerepar;Cinarizine;Cinnacet;Cinnipirine;Denapol;Dimitronal;Folcodal;Glanil;Ixterol;Labyrin;Marisan;Mitronal;Olamin;Sepan;Spaderizine;Stutgeron;Toliman;

Identification
NamePiperazine,1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)-
CAS298-57-7
SynonymsPiperazine,1-cinnamyl-4-(diphenylmethyl)- (6CI,7CI,8CI);1-(3-Phenylallyl)-4-(diphenylmethyl)piperazine;1-Cinnamyl-4-(diphenylmethyl)piperazine;1-Diphenylmethyl-4-cinnamoylpiperazine;516MD;Aplactan;Apotomin;Carecin;Cerepar;Cinarizine;Cinnacet;Cinnipirine;Denapol;Dimitronal;Folcodal;Glanil;Ixterol;Labyrin;Marisan;Mitronal;Olamin;Sepan;Spaderizine;Stutgeron;Toliman;
EINECS(EC#)206-064-8
Molecular FormulaC26H28N2
Molecular Weight368.56
Chemical Properties
Appearancewhite powder
refractive index1.649
storage tempRefrigerator
Safety Data

Hazard Xn
Risk R20/22
Safety

Poison by intravenous route. Moderately toxic by intraperitoneal route. Experimental reproductive effects. Human systemic effects by ingestion: allergic dermatitis. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:Xn
Risk Statements:
20: ?Harmful by inhalation?
22: ?Harmful if swallowed?
36: ?Irritating to the eyes
37: ?Irritating to the respiratory system
38: ?Irritating to the skin
42: ?May cause sensitization by inhalation
43: ?May cause sensitization by skin contact?
Safety Statements:
22: ?Do not breathe dust
24: ?Avoid contact with skin
25: ?Avoid contact with eyes
26: ?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36: ?Wear suitable protective clothing


Toxicity
1. ???

orl-wmn TDLo:252?mg/kg/12W-I:SKN

??? BJDEAZ ?? British Journal of Dermatology. 112 (1985),607.
2. ???

ipr-rat LD50:1050?mg/kg

??? MDACAP ?? Medicamentos de Actualidad. 21 (1985),443.
3. ???

ivn-rat LD50:24?mg/kg

??? KSRNAM ?? Kiso to Rinsho. Clinical Report. 16 (1982),1735.
4. ???

ipr-mus LD50:730?mg/kg

??? MDACAP ?? Medicamentos de Actualidad. 21 (1985),443.
5. ???

ivn-mus LD50:22?mg/kg

??? KSRNAM ?? Kiso to Rinsho. Clinical Report. 16 (1982),1735.

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Saniver Limited
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INFA S.P.A.
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Hangzhou Starshine Pharmaceutical Co., LTD
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Zhejiang Yulong Chemical Co.,Ltd.
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Transo-Pharm
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NORBRIGHT INDUTRY CO., LTD
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Hikal Ltd.
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Fleming Laboratories Limited
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Varda Biotech Pvt. Ltd.
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Conier Chem & Pharma Co.,Ltd.
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Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,
AOKChem Co., Ltd.
Tel:+86-(21)-50791030 / 68712331
Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,
Parchem - Fine & Specialty Chemicals
Tel:+1-(914)-654-6800, 800-282-3982
Address: 415 Huguenot Street, New Rochelle, New York 10801,
Huiena(tianjin) Chemical Co., Ltd.
Tel:0311-67698362
Address: tianjin China
HuaiBei SanHe Developing Co., Ltd.
Tel:86-561-3191113
Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China
Yarong Chemical Development Ltd
Tel:+86-755-89707236
Address: Shenzhen,China

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