Sparteine sulfate cas no:299-39-8

NameSparteine sulfate
CAS299-39-8
Synonyms7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-;Spartin;Tocosamine sulfate;Siarczan sparteiny
EINECS(EC#)206-078-4
Molecular FormulaC₁₅H₂₆N₂ . H₂O₄S
Molecular Weight332.51

Hazardclass6.1(b)

Risk 23/25-33
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human reproductive effects by intramuscular route: stillbirth; changes in uterus, cervix and vagina. When heated to decomposition it emits toxic fumes of NO_x and SO_x.
Risk Statements 23/25-33
R23/25:Toxic by inhalation and if swallowed. 
R33:Danger of cumulative effects.
Safety Statements 1-45
S1 :Keep locked up. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 1544
HazardClass 6.1(b)
PackingGroup III

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	parenteral	375mg/kg (375mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 431, 1926.
guinea pig	LDLo	intraperitoneal	42mg/kg (42mg/kg)		Journal of Agricultural Research Vol. 32, Pg. 51, 1926.
mouse	LD50	intraperitoneal	43mg/kg (43mg/kg)		Journal of Medicinal Chemistry. Vol. 20, Pg. 1668, 1977.
mouse	LD50	intravenous	15mg/kg (15mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: STIFFNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.
mouse	LD50	oral	350mg/kg (350mg/kg)	BEHAVIORAL: EXCITEMENT	Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1497, 1980.
mouse	LD50	subcutaneous	117mg/kg (117mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: STIFFNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.
rabbit	LDLo	subcutaneous	80mg/kg (80mg/kg)	VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION	Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 431, 1926.
rat	LD50	intravenous	30400ug/kg (30.4mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: STIFFNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.