1,2,3,4-Butanetetrol,1,4-dimethanesulfonate, (2S,3S)- cas no:299-75-2

Synonyms: 1,2,3,4-Butanetetrol,1,4-dimethanesulfonate,[S-(R*,R*)]-;Threitol,1,4-dimethanesulfonate,(2S,3S)- (8CI);(2S,3S)-Threitol 1,4-bismethanesulfonate;L-Threitol1,4-bis(methanesulfonate);NSC 39069;Ovastat;Threosulphan;Treosulfan

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Identification
Chemical Properties
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Safety Data
Toxicity

Identification

Name1,2,3,4-Butanetetrol,1,4-dimethanesulfonate, (2S,3S)-
CAS299-75-2
Synonyms1,2,3,4-Butanetetrol,1,4-dimethanesulfonate,[S-(R*,R*)]-;Threitol,1,4-dimethanesulfonate,(2S,3S)- (8CI);(2S,3S)-Threitol 1,4-bismethanesulfonate;L-Threitol1,4-bis(methanesulfonate);NSC 39069;Ovastat;Threosulphan;Treosulfan
EINECS(EC#)206-081-0
Molecular FormulaC6H14 O8 S2
Molecular Weight246.32

Chemical Properties

refractive index1.518

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

Confirmed carcinogen. Poison by intravenous route. Human mutation data reported. When heated to decomposition it emits toxic fumes of SO_x.
RIDADR 2811
HazardClass 6.1(b)
PackingGroup III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	222mg/kg (222mg/kg)	GASTROINTESTINAL: OTHER CHANGES BLOOD: LEUKOPENIA BLOOD: OTHER CHANGES	Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 203, 1965.
monkey	LDLo	intravenous	222mg/kg (222mg/kg)	BLOOD: LEUKOPENIA BLOOD: AGRANULOCYTOSIS BLOOD: OTHER CHANGES	Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 203, 1965.

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