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9H-Purin-6-amine,9-(5-O-phosphono-b-D-arabinofuranosyl)- cas no:29984-33-6

Synonyms: Adenine,9-b-D-arabinofuranosyl-,5'-(dihydrogen phosphate) (8CI);5'-Arabinosyladenine monophosphate;9-b-D-Arabinofuranosyl AMP;9-b-D-Arabinofuranosyladenine5'-monophosphate;9-b-D-Arabinofuranosyladenine 5'-phosphate;9-b-D-Arabinofuranosyladenine monophosphate;Adeninearabinonucleoside 5'-phosphate;Adenine arabinoside 5'-monophosphate;Adenine arabinosidemonophosphate;Arabinosyladenine monophosphate;CI 808;D-Arabinosyladenine5'-monophosphate;NSC 127223;Vidarabine phosphate;Vidarabine-5'-monophosphate;ara-AMP;

Identification
Name9H-Purin-6-amine,9-(5-O-phosphono-b-D-arabinofuranosyl)-
CAS29984-33-6
SynonymsAdenine,9-b-D-arabinofuranosyl-,5'-(dihydrogen phosphate) (8CI);5'-Arabinosyladenine monophosphate;9-b-D-Arabinofuranosyl AMP;9-b-D-Arabinofuranosyladenine5'-monophosphate;9-b-D-Arabinofuranosyladenine 5'-phosphate;9-b-D-Arabinofuranosyladenine monophosphate;Adeninearabinonucleoside 5'-phosphate;Adenine arabinoside 5'-monophosphate;Adenine arabinosidemonophosphate;Arabinosyladenine monophosphate;CI 808;D-Arabinosyladenine5'-monophosphate;NSC 127223;Vidarabine phosphate;Vidarabine-5'-monophosphate;ara-AMP;
EINECS(EC#)249-990-8
Molecular FormulaC10H14N5O7P
Molecular Weight347.22
Chemical Properties
AppearanceWhite crystalline powder.
storage tempStore at 0°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard Xn:Harmful;
Risk R20/22
Safety

Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of POx and NOx.
 

Hazard Codes: Xn,T,Xi
Risk Statements:
20:  Harmful by inhalation
22:  Harmful if swallowed 
23:  Toxic by inhalation
24:  Toxic in contact with skin
25:  Toxic if swallowed
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
40:  Limited evidence of a carcinogenic effect
Safety Statements:
22:  Do not breathe dust
24:  Avoid contact with skin
25:  Avoid contact with eyes
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing 
37:  Wear suitable gloves
39:  Wear eye/face protection
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)


Toxicity
1.    

ipr-rat LD50:1700 mg/kg

    DRFUD4    Drugs of the Future. 4 (1979),547.
2.    

ipr-mus LD50:1200 mg/kg

    DRFUD4    Drugs of the Future. 4 (1979),547.

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Melone Pharmaceutical Co., Ltd.
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AOKChem Co., Ltd.
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Shanghai Xunxin Chemical Co., Ltd
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China Langchem Inc.
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Harlan China
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Shanghai Oripharm Co., Ltd
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Shanghai Degu Pharmaceutical Tech Co., Ltd
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