D-ribo-Hexitol,2,5-anhydro-1,4,6-trideoxy-6-(trimethylammonio)- cas no:300-54-9

NameD-ribo-Hexitol,2,5-anhydro-1,4,6-trideoxy-6-(trimethylammonio)-
CAS300-54-9
Synonyms2-Furanmethanaminium,tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, [2S-(2a,4b,5a)]-; Muscarine (alkaloid) (8CI);(+)-(2S,4R,5S)-Muscarine; (+)-Muscarine; L-(+)-Muscarine; Muscarine; [2S-(2a,4b,5a)]-(Tetrahydro-4-hydroxy-5-methylfurfuryl)trimethylammonium
EINECS(EC#)206-094-1
Molecular FormulaC9H20 N O2
Molecular Weight174.30

Hazard Xn: Harmful;
Risk 22-36
Safety

The Hazard Codes of Muscarine (CAS NO.300-54-9):Xn
Risk Statements:R22:Harmful if swallowed. R36:Irritating to eyes.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
Human poison by an unspecified route. Experimental poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NO_x and NH₃.

The toxicity of Muscarine (CAS NO.300-54-9):

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	1100ug/kg (1.1mg/kg)		Science. Vol. 144, Pg. 1100, 1964. Link to PubMed
cat	LDLo	oral	7mg/kg (7mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
cat	LDLo	subcutaneous	2mg/kg (2mg/kg)		"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 406, 1948.
frog	LDLo	parenteral	160ug/kg (0.16mg/kg)		Justus Leibigs Annalen der Chemie. Vol. 489, Pg. 156, 1931.
frog	LDLo	unreported	160ug/kg (0.16mg/kg)		"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 407, 1948.
man	LDLo	unreported	735ug/kg (0.735mg/kg)		"Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse	LD50	intraperitoneal	5mg/kg (5mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 192, Pg. 88, 1971.
mouse	LD50	intravenous	230ug/kg (0.23mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Toxicology Letters. Vol. 1000(Sp,
mouse	LD50	subcutaneous	1100ug/kg (1.1mg/kg)		Naturwissenschaften. Vol. 56, Pg. 615, 1969.
mouse	LDLo	oral	750mg/kg (750mg/kg)		"Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 167, 1973.
rabbit	LDLo	oral	150mg/kg (150mg/kg)	VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 61, Pg. 283, 1909.
rabbit	LDLo	subcutaneous	27mg/kg (27mg/kg)		Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 61, Pg. 283, 1909.