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Chloral hydrate cas no:302-17-0

Synonyms: 1,1,1-trichloro-2,2-ethanediol; 2,2,2-Trichloro-1,1-ethanediol; aquachloral; bi 3411; chloraldurat; dormal; Escre; felsules; hydral; kessodrate; lorinal; Noctec; nortec; nycoton; nycton; phaldrone; rectules; sk-chloral hydrate; somni sed; somnos; sontec; trawotox; trichloroacetaldehyde hydrate; Trichloroacetaldehyde Monohydrate; TCA

Identification
NameChloral hydrate
CAS302-17-0
Synonyms1,1,1-trichloro-2,2-ethanediol; 2,2,2-Trichloro-1,1-ethanediol; aquachloral; bi 3411; chloraldurat; dormal; Escre; felsules; hydral; kessodrate; lorinal; Noctec; nortec; nycoton; nycton; phaldrone; rectules; sk-chloral hydrate; somni sed; somnos; sontec; trawotox; trichloroacetaldehyde hydrate; Trichloroacetaldehyde Monohydrate; TCA
EINECS(EC#)206-117-5
Molecular FormulaC2H3Cl3O2
Molecular Weight165.4
Chemical Properties
Appearancewhite crystalline powde
Safety Data

Hazard T:Toxic
Risk R25;R36/38
Safety

A human poison by ingestion and possibly other routes. Poison experimentally by ingestion, intravenous, and rectal routes. Moderately toxic by subcutaneous, parenteral, and intraperitoneal routes. Experimental reproductive effects. Human systemic effects by ingestion: general anesthetic, cardiac arrhythmias, blood pressure depression, eye effects, coma, pulse rate increase, arrhythmias. Human mutation data reported. Questionable carcinogen with experimental carcinogenic and tumorigenic data by skin contact. A sedative, anesthetic, and narcotic. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl?.
Hazard Codes:?ToxicTFlammableF
Risk Statements: 25-36/38-39-23/24/25-11-36/37/38?
R25 :Toxic if swallowed.?
R36/38:Irritating to eyes and skin.?
R39:Danger of very serious irreversible effects.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R11:Highly flammable.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-45-25-23-36/37-16-27?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S25:Avoid contact with eyes.?
S23:Do not breathe vapour.?
S36/37:Wear suitable protective clothing and gloves.?
S16:Keep away from sources of ignition.?
S27:Take off immediately all contaminated clothing.
RIDADR: UN 3286 3/PG 2
WGK Germany: 2
RTECS: FM8750000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

mrc-smc 15?mmol/L

??? MUREAV ?? Mutation Research. 141 (1984),19.
2. ???

sce-hmn:lym 54?mg/L

??? AGTQAH ?? Annales de Genetique. 24 (1981),105.
3. ???

orl-mus TDLo:10?mg/kg:CAR

??? CDPRD4 ?? Cancer Detection and Prevention. 9 (1986),279.
4. ???

orl-wmn TDLo:465?mg/kg:EYE,BPR

??? AMSVAZ ?? Acta Medica Scandinavica. 223 (1988),269.
5. ???

orl-hmn LDLo:4?mg/kg

??? PHBTH* ?? Pharmacology: Basis of Therapy. 3 (1967),132.
6. ???

orl-hmn TDLo:300?mg/kg:CNS,CVS

??? BMJOAE ?? British Medical Journal. 2 (1977),994.
7. ???

unr-cld TDLo:48?mg/kg/6H-I:BPR AACRAT 65,691,86

8. ???

unk-man LDLo:103?mg/kg

??? 85DCAI ?? Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73.
9. ???

unr-inf TDLo:160?mg/kg/3D-I:CVS AACRAT 65,691,86

10. ???

rec-cld TDLo:97?mg/kg:CVS AACRAT 65,691,86

11. ???

orl-rat LD50:479?mg/kg

??? TXAPA9 ?? Toxicology and Applied Pharmacology. 18 (1971),185.
12. ???

skn-rat LD50:3030?mg/kg

??

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Beijing Fengli Jingqiu Trade Co., Ltd.
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Shanghai Experiment Reagent Co.,LTD.
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Bulk Pharmaceuticals Inc.
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Applichem GmbH
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Chemner Pharma
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Qinhuangdao Bright Chemical Co., Ltd
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Ruger Chemical Co. Ltd.
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Goly Chemical Co., Ltd.
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Bright Chemicals Ltd
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Triveni Chemicals
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Advanced Technology & Industrial Co., Ltd.
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China Langchem Inc.
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Wuhan Star Trading Co., Ltd
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Address: No.498, Jianshe Ave, Wuhan, China

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