302-95-4|Cholan-24-oic acid,3,12-dihydroxy-, monosodium salt, (3a,5b,12a)-Products Supply

Cholan-24-oic acid,3,12-dihydroxy-, monosodium salt, (3a,5b,12a)- cas no:302-95-4

Synonyms: 5b-Cholan-24-oic acid, 3a,12a-dihydroxy-, monosodium salt (8CI);Deoxycholic acidmonosodium salt;Deoxycholic acid sodium salt;Desoxycholate sodium;Desoxycholic acid sodium salt;NSC 681065;Sodium 3a,12a-dihydroxy-5b-cholanate;Sodium 7-deoxycholate;Sodium deoxycholate;Sodium desoxycholate;Sodium Deoxycholic acid;

Identification

NameCholan-24-oic acid,3,12-dihydroxy-, monosodium salt, (3a,5b,12a)-
CAS302-95-4
Synonyms5b-Cholan-24-oic acid, 3a,12a-dihydroxy-, monosodium salt (8CI);Deoxycholic acidmonosodium salt;Deoxycholic acid sodium salt;Desoxycholate sodium;Desoxycholic acid sodium salt;NSC 681065;Sodium 3a,12a-dihydroxy-5b-cholanate;Sodium 7-deoxycholate;Sodium deoxycholate;Sodium desoxycholate;Sodium Deoxycholic acid;
EINECS(EC#)206-132-7
Molecular FormulaC₂₄H₃₉NaO₄
Molecular Weight414.56

Chemical Properties

Appearancecream crystalline powder.
alpha44 º (C=2, H2O)

Safety Data

Hazard Xn:Harmful;
Risk R22
Safety

Hazard Codes of Sodium deoxycholate (CAS NO.302-95-4): Xn
Risk Statements: 22-37
22: Sodium desoxycholate (302-95-4) is harmful if swallowed
37: Irritating to the respiratory system
Safety Statements: 22
22: Harmful if swallowed
WGK Germany: 3
RTECS: FZ2250000
F: 3-10
HS Code: 29181930

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	36mg/kg (36mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29, 1985.
mouse	LD50	intravenous	107mg/kg (107mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 90, Pg. 18, 1952.
mouse	LD50	oral	1050mg/kg (1050mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29, 1985.
mouse	LD50	subcutaneous	815mg/kg (815mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
rabbit	LDLo	intravenous	15mg/kg (15mg/kg)	CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: OTHER CHANGES	Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 52, Pg. 779, 1926.
rat	LD50	intraperitoneal	123mg/kg (123mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
rat	LD50	intravenous	150mg/kg (150mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 323, 1970.
rat	LD50	oral	1370mg/kg (1370mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
rat	LD50	subcutaneous	2430mg/kg (2430mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.

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Cholan-24-oic acid,3,12-dihydroxy-, monosodium salt, (3a,5b,12a)- cas no:302-95-4

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