Butanoic acid,2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methyl-,[(1S,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S)- cas no:303-33-3

NameButanoic acid,2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methyl-,[(1S,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S)-
CAS303-33-3
SynonymsButanoicacid, 2-hydroxy-2-(1-methoxyethyl)-3-methyl-,(2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, [1S-[1a,7[R*(S*)],7aa]]-; Heliotrine (6CI,8CI);(+)-Heliotrine; 7S-Heliotrine
Molecular FormulaC16H27 N O5
Molecular Weight313.44

refractive index1.541

Safety

A poison by ingestion, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Safety Statements: 22-36/37/39-45 
S22: Do not breathe dust. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
HazardClass: 6.1(b)
RIDADR: 1544
PackingGroup: III

1.		mma-sat 1 mg/plate		MUREAV    Mutation Research. 68 (1979),211.
2.		dni-hmn:lvr 25 mg/L		IJEVAW    International Journal of Environmental Studies. 1 (1971),107.
3.		oms-hmn:lvr 10 mg/L		IJEVAW    International Journal of Environmental Studies. 1 (1971),107.
4.		sce-ham:lng 1200 µg/L		MUREAV    Mutation Research. 142 (1985),209.
5.		cyt-mam:leu 50 µmol/L		AJBSAM    Australian Journal of Biological Sciences. 21 (1968),469.
6.		orl-rat LDLo:50 mg/kg		NATUAS    Nature. 179 (1957),361.
7.		ipr-rat LD50:296 mg/kg		JPBAA7    Journal of Pathology and Bacteriology. 75 (1958),17.
8.		ivn-rat LD50:274 mg/kg		AMPLAO    AMA Archives of Pathology. 64 (1957),152.
9.		ivn-mus LD50:251 mg/kg		AMPLAO    AMA Archives of Pathology. 64 (1957),152.
10.		ipr-mus LD50:296 mg/kg		JPBAA7    Journal of Pathology and Bacteriology. 75 (1958),17.
11.		ipr-mam LDLo:250 mg/kg