10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine,N,N-dimethyl- cas no:303-69-5

Synonyms: 10-(3-Dimethylaminopropyl)-10H-pyrido[3,2-b][1,4]benzothiazine;2,3-Pyridino-(5',6')-5,6-benzo-4-(3''-dimethylaminopropyl)-1,4-thiazine;Dominal;LG 206;Largophren;MH 05101;Phrenotropin;Prothipendyl;Timoval;Timovan;Tumovan

Identification

Name10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine,N,N-dimethyl-
CAS303-69-5
Synonyms10-(3-Dimethylaminopropyl)-10H-pyrido[3,2-b][1,4]benzothiazine;2,3-Pyridino-(5',6')-5,6-benzo-4-(3''-dimethylaminopropyl)-1,4-thiazine;Dominal;LG 206;Largophren;MH 05101;Phrenotropin;Prothipendyl;Timoval;Timovan;Tumovan
EINECS(EC#)214-958-4
Molecular FormulaC16H19 N3 S
Molecular Weight285.44

Chemical Properties

refractive index1.621

Safety Data

Safety

Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.

Toxicity

1.	ivn-rat LD50:25 mg/kg	THERAP Therapie. 18 (1963),373.
2.	orl-mus LD50:415 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),489.
3.	ipr-mus LD50:155 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),489.
4.	scu-mus LD50:102 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),374.

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