304-20-1|Hydralazine hydrochlorideProducts Supply - Chemical intermediates Network

Hydralazine hydrochloride cas no:304-20-1

Synonyms: 1(2H)-Phthalazinone hydrazone; 1-Hydrazinophthalazine hydrochloride

Identification

NameHydralazine hydrochloride
CAS304-20-1
Synonyms1(2H)-Phthalazinone hydrazone; 1-Hydrazinophthalazine hydrochloride
EINECS(EC#)206-151-0
Molecular FormulaC8H8N4?HCl;C8H9ClN4
Molecular Weight160.17592

Chemical Properties

AppearanceWhite Crystalline Solid

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard Xn:Harmful
Risk R22;R36/37/38
Safety

Suspected carcinogen with experimental neoplastigenic data. A poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human mutation data reported. An experimental teratogen. An antihypertensive agent. When heated to decomposition it emits very toxic NO_x and HCl.
Hazard Codes:
Xn: Harmful
Risk Statements about Hydralazine hydrochloride (304-20-1):
R22 Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Hydralazine hydrochloride (304-20-1):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.

Toxicity

1.	mmo-sat 500 µg/plate	RCOCB8 Research Communications in Chemical Pathology and Pharmacology. 49 (1985),415.
2.	dni-hmn:hla 150 µmol/L	MUREAV Mutation Research. 92 (1982),427.
3.	orl-mus TDLo:2950 mg/kg/78W-C:NEO	JJIND8 JNCI, Journal of the National Cancer Institute. 61 (1978),1363.
4.	ivn-rat LD50:34 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),619.
5.	orl-mus LD50:188 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 3 (1969),97.
6.	ipr-mus LD50:83 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 101 (1951),368.
7.	scu-mus LD50:73 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),619.
8.	ivn-mus LD50:84 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 3 (1969),97.

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HangZhou Peak Chemical Co.,Ltd: Tel:+86-571-88233073; Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

Hydralazine hydrochloride cas no:304-20-1

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