Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2) cas no:30484-77-6
Synonyms: Piperazine,1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-;Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-,dihydrochloride (9CI);Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-,dihydrochloride, (E)- (8CI);(E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazinedihydrochloride;Dinaplex;Flugeral;Flunagen;Flunarizine hydrochloride;Flunarl;Fluxarten;Gradient;Issium;Mondus;R14950;
NamePiperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2)
CAS30484-77-6
SynonymsPiperazine,1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-;Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-,dihydrochloride (9CI);Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-,dihydrochloride, (E)- (8CI);(E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazinedihydrochloride;Dinaplex;Flugeral;Flunagen;Flunarizine hydrochloride;Flunarl;Fluxarten;Gradient;Issium;Mondus;R14950;
EINECS(EC#)250-216-6
Molecular FormulaC26H28Cl2F2N2
Molecular Weight404.494846
AppearanceWhite crystalline powder, odorless and tasteless
storage temp2-8°C
Hazard Xn:Harmful;
Risk R22
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl−, NOx, and F−.
Hazard Codes:
Xn: Harmful .gif)
Risk Statements about Flunarizine dihydrochloride (CAS No.:30484-77-6):
R22 Harmful if swallowed.
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orl-rat LD50:503 mg/kg
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ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1408. |
| 2. |
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ipr-rat LD50:305 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825. |
| 3. |
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scu-rat LD50:1793 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825. |
| 4. |
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ivn-rat LD50:35 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825. |
| 5. |
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orl-mus LD50:1203 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825. |
| 6. |
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ipr-mus LD50:379 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825. |
| 7. |
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ivn-mus LD50:27 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825. |
