30484-77-6|Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2)Products Supply

Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2) cas no:30484-77-6

Synonyms: Piperazine,1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-;Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-,dihydrochloride (9CI);Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-,dihydrochloride, (E)- (8CI);(E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazinedihydrochloride;Dinaplex;Flugeral;Flunagen;Flunarizine hydrochloride;Flunarl;Fluxarten;Gradient;Issium;Mondus;R14950;

Identification

NamePiperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2)
CAS30484-77-6
SynonymsPiperazine,1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-;Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-,dihydrochloride (9CI);Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-,dihydrochloride, (E)- (8CI);(E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazinedihydrochloride;Dinaplex;Flugeral;Flunagen;Flunarizine hydrochloride;Flunarl;Fluxarten;Gradient;Issium;Mondus;R14950;
EINECS(EC#)250-216-6
Molecular FormulaC₂₆H₂₈Cl₂F₂N₂
Molecular Weight404.494846

Chemical Properties

AppearanceWhite crystalline powder, odorless and tasteless
storage temp2-8°C

Safety Data

Hazard Xn:Harmful;
Risk R22
Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl⁻, NO_x, and F⁻.
Hazard Codes:
Xn: Harmful
Risk Statements about Flunarizine dihydrochloride (CAS No.:30484-77-6):
R22 Harmful if swallowed.

Toxicity

1.	orl-rat LD50:503 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1408.
2.	ipr-rat LD50:305 mg/kg	YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825.
3.	scu-rat LD50:1793 mg/kg	YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825.
4.	ivn-rat LD50:35 mg/kg	YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825.
5.	orl-mus LD50:1203 mg/kg	YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825.
6.	ipr-mus LD50:379 mg/kg	YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825.
7.	ivn-mus LD50:27 mg/kg	YKYUA6 Yakkyoku. Pharmacy. 36 (1985),825.

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Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2) cas no:30484-77-6

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