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L-Carnosine cas no:305-84-0

Synonyms: beta-Alanyl-L-histidine;L-Carnosine 99% min.;N-2-M;L-Carnosinc;β-Alanyl-L-histidine;L-Carnosine Acetate;Karnozin;2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid;L-Histidine, N-.beta.-alanyl-;Nalpha-(beta-alanyl)-L-histidine;(2S)-2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid;.beta.-Alanyl-L-histidine;Ignotine;

Identification
NameL-Carnosine
CAS305-84-0
Synonymsbeta-Alanyl-L-histidine;L-Carnosine 99% min.;N-2-M;L-Carnosinc;β-Alanyl-L-histidine;L-Carnosine Acetate;Karnozin;2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid;L-Histidine, N-.beta.-alanyl-;Nalpha-(beta-alanyl)-L-histidine;(2S)-2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid;.beta.-Alanyl-L-histidine;Ignotine;
EINECS(EC#)206-169-9
Molecular FormulaC9H14N4O3
Molecular Weight226.23
Chemical Properties
Appearancecrystalline
alpha20.9 o (C=1.5, H2O)
refractive index21 ° (C=2, H2O)
storage temp2-8°C
Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Mildly toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
The Hazard Codes of CARNOSINE(305-84-0): ? Xn
The Risk Statements information of Carnosine (305-84-0): 20/21/22-36/37/38
20/21/22:? Harmful by inhalation, in contact with skin and if swallowed?
36/37/38:? Irritating to eyes, respiratory system and skin?
The Safety Statements information of Carnosine (305-84-0): 24/25-36-26
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
24/25:? Avoid contact with skin and eyes?
WGK Germany: 2
RTECS: MS3080000
F: 3-10


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 9087mg/kg (9087mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
United States Patent Document. Vol. #4446149,
mouse LD50 oral > 14930mg/kg (14930mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
United States Patent Document. Vol. #4446149,
LD50/LC50: RTECS:
CAS# 305-84-0: Oral, mouse: LD50 = >14930 mg/kg;
Carcinogenicity: L-Carnosine - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other: The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information.
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