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Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(2-hydroxyethoxy)ethyl ester cas no:30544-47-9

Synonyms: Anthranilicacid, N-(a,a,a-trifluoro-m-tolyl)-, 2-(2-hydroxyethoxy)ethyl ester (8CI);2-(2-Hydroxyethoxy)ethyl flufenamate;2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid 2-(2-hydroxyethoxy)ethylester; B 577; Bay-d 1107; Bayrogel; Etofenamate; Glasel; Reumon; Rheumon;Rheumon gel; TV 485; Traumon Gel; WHR 5020

Identification
NameBenzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(2-hydroxyethoxy)ethyl ester
CAS30544-47-9
SynonymsAnthranilicacid, N-(a,a,a-trifluoro-m-tolyl)-, 2-(2-hydroxyethoxy)ethyl ester (8CI);2-(2-Hydroxyethoxy)ethyl flufenamate;2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid 2-(2-hydroxyethoxy)ethylester; B 577; Bay-d 1107; Bayrogel; Etofenamate; Glasel; Reumon; Rheumon;Rheumon gel; TV 485; Traumon Gel; WHR 5020
EINECS(EC#)250-231-8
Molecular FormulaC18H18 F3 N O4
Molecular Weight369.33
Chemical Properties
refractive index1.552
Safety Data

Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous routes. Experimental teratogenic and reproductive effects. Used as an anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of F and NOx. See also FLUORIDES.


Toxicity
1.    

orl-rat LD50:292 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1333.
2.    

ipr-rat LD50:373 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1333.
3.    

scu-rat LD50:568 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1333.
4.    

ivn-rat LD50:139 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225.
5.    

orl-mus LD50:743 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1333.
6.    

scu-mus LD50:1897 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225.
7.    

ivn-mus LD50:75 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225.
8.    

scu-rbt LD50:1532 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225.

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