Geldanamycin cas no:30562-34-6
Synonyms: 2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, 9-carbamate (8CI);(+)-Geldanamycin;2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9-[(aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-,[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-;NSC 122750;NSC 212518;[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-9-[(Aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione;
NameGeldanamycin
CAS30562-34-6
Synonyms2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, 9-carbamate (8CI);(+)-Geldanamycin;2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9-[(aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-,[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-;NSC 122750;NSC 212518;[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-9-[(Aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione;
Molecular FormulaC29H40N2O9
Molecular Weight560.6359
Appearanceyellow to orange powder
refractive index1.559
storage temp−20°C
Hazard T: Toxic;
Risk R36/37/38
Safety
Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Safety Information about (3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-Hydroxy-5,11,21-trimethoxy-3,7,9,
15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,
14,18-pentaen-10-yl] carbamate (30562-34-6):
Hazard Codes:
T: Xi:
Risk Statements
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27: Take off immediately all contaminated clothing.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany:2
RTECS:LX8920000
| 1. |
|
dni-mus:lym 1 mg/L
|
|
JANTAJ Journal of Antibiotics. 35 (1982),886. |
| 2. |
|
orl-rat LD50:2500 mg/kg
|
|
85ERAY Antibiotics: Origin, Nature, and Properties. 1 (1978),820. |
| 3. |
|
ipr-mus LD50:1 mg/kg
|
|
UPJOH* Compounds Available for Fundamental Research. 2 (6)(1971), |
