dog |
LD50 |
intravenous |
60mg/kg (60mg/kg) |
|
Medicamentos de Actualidad. Vol. 18, Pg. 310, 1982. |
dog |
LD50 |
oral |
100mg/kg (100mg/kg) |
|
Medicamentos de Actualidad. Vol. 18, Pg. 310, 1982. |
mouse |
LD50 |
intravenous |
24100ug/kg (24.1mg/kg) |
|
Drugs in Japan Vol. -, Pg. 72, 1995. |
mouse |
LD50 |
oral |
1330mg/kg (1330mg/kg) |
behavioral: altered sleep time (including change in righting reflex) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16, Pg. 1471, 1988. |
mouse |
LD50 |
subcutaneous |
282mg/kg (282mg/kg) |
|
Drugs in Japan Vol. -, Pg. 72, 1995. |
rabbit |
LD50 |
intravenous |
25mg/kg (25mg/kg) |
|
Medicamentos de Actualidad. Vol. 18, Pg. 310, 1982. |
rabbit |
LD50 |
oral |
800mg/kg (800mg/kg) |
|
Medicamentos de Actualidad. Vol. 18, Pg. 310, 1982. |
rat |
LD50 |
intravenous |
24mg/kg (24mg/kg) |
behavioral: altered sleep time (including change in righting reflex) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16, Pg. 1471, 1988. |
rat |
LD50 |
oral |
1330mg/kg (1330mg/kg) |
|
Drugs in Japan Vol. -, Pg. 72, 1995. |
rat |
LD50 |
subcutaneous |
282mg/kg (282mg/kg) |
behavioral: altered sleep time (including change in righting reflex) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea
|
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16, Pg. 1471, 1988. |