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4(1H)-Pyridinone,3-hydroxy-1,2-dimethyl- cas no:30652-11-0

Synonyms: 4(1H)-Pyridone,3-hydroxy-1,2-dimethyl- (8CI);1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone;1,2-Dimethyl-3-hydroxypyridin-4-one;1,2-Dimethyl-3-hydroxypyridine-4-one;3-Hydroxy-1,2-dimethyl-4(1H)-pyridinone;3-Hydroxy-1,2-dimethyl-4(1H)-pyridone;3-Hydroxy-1,2-dimethyl-4-pyridinone;3-Hydroxy-1,2-dimethyl-4-pyridone;APO 66;CGP 37391;CP 20 (chelatingagent);DN 18001AF;Deferiprone;Ferriprox;L 1 (chelatingagent);

Identification
Name4(1H)-Pyridinone,3-hydroxy-1,2-dimethyl-
CAS30652-11-0
Synonyms4(1H)-Pyridone,3-hydroxy-1,2-dimethyl- (8CI);1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone;1,2-Dimethyl-3-hydroxypyridin-4-one;1,2-Dimethyl-3-hydroxypyridine-4-one;3-Hydroxy-1,2-dimethyl-4(1H)-pyridinone;3-Hydroxy-1,2-dimethyl-4(1H)-pyridone;3-Hydroxy-1,2-dimethyl-4-pyridinone;3-Hydroxy-1,2-dimethyl-4-pyridone;APO 66;CGP 37391;CP 20 (chelatingagent);DN 18001AF;Deferiprone;Ferriprox;L 1 (chelatingagent);
EINECS(EC#)212-783-8
Molecular FormulaC7H9NO2
Molecular Weight139.15
Chemical Properties
AppearanceWhite needles
refractive index1.564
Safety Data

Hazard Xn:Harmful;
Risk R22;R36/37/38
Safety

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.
Hazard Codes:
Xn: Harmful
Risk Statements about 1,2-Dimethyl-3-hydroxypyrid-4-one (30652-11-0):
R22 Harmful if swallowed. 
R36/37/38 Irritating to eyes, respiratory system and skin. 
Safety Statements about 1,2-Dimethyl-3-hydroxypyrid-4-one (30652-11-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39 Wear suitable gloves and eye/face protection.
Attentions:
1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo oral 1gm/kg (1000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: FOOD INTAKE (ANIMAL)

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
BioMetals. Vol. 10, Pg. 247, 1997.
mammal (species unspecified) LD50 unreported > 1gm/kg (1000mg/kg)   Archives of Toxicology, Supplement. Vol. 18, Pg. 202, 1996.
mouse LD50 intraperitoneal 983mg/kg (983mg/kg)   Blood. Vol. 76, Pg. 2389, 1990.
rat LD50 intraperitoneal 600mg/kg (600mg/kg)   Drugs of the Future. Vol. 13, Pg. 413, 1988.
rat LD50 oral 2gm/kg (2000mg/kg) CARDIAC: OTHER CHANGES Archives of Toxicology, Supplement. Vol. 18, Pg. 202, 1996.
 

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