4(1H)-Pyridinone,3-hydroxy-1,2-dimethyl- cas no:30652-11-0
Synonyms: 4(1H)-Pyridone,3-hydroxy-1,2-dimethyl- (8CI);1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone;1,2-Dimethyl-3-hydroxypyridin-4-one;1,2-Dimethyl-3-hydroxypyridine-4-one;3-Hydroxy-1,2-dimethyl-4(1H)-pyridinone;3-Hydroxy-1,2-dimethyl-4(1H)-pyridone;3-Hydroxy-1,2-dimethyl-4-pyridinone;3-Hydroxy-1,2-dimethyl-4-pyridone;APO 66;CGP 37391;CP 20 (chelatingagent);DN 18001AF;Deferiprone;Ferriprox;L 1 (chelatingagent);
Name4(1H)-Pyridinone,3-hydroxy-1,2-dimethyl-
CAS30652-11-0
Synonyms4(1H)-Pyridone,3-hydroxy-1,2-dimethyl- (8CI);1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone;1,2-Dimethyl-3-hydroxypyridin-4-one;1,2-Dimethyl-3-hydroxypyridine-4-one;3-Hydroxy-1,2-dimethyl-4(1H)-pyridinone;3-Hydroxy-1,2-dimethyl-4(1H)-pyridone;3-Hydroxy-1,2-dimethyl-4-pyridinone;3-Hydroxy-1,2-dimethyl-4-pyridone;APO 66;CGP 37391;CP 20 (chelatingagent);DN 18001AF;Deferiprone;Ferriprox;L 1 (chelatingagent);
EINECS(EC#)212-783-8
Molecular FormulaC7H9NO2
Molecular Weight139.15
AppearanceWhite needles
refractive index1.564
Hazard Xn:Harmful;
Risk R22;R36/37/38
Safety
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.
Hazard Codes:
Xn: Harmful .gif)
Risk Statements about 1,2-Dimethyl-3-hydroxypyrid-4-one (30652-11-0):
R22 Harmful if swallowed.
R36/37/38 Irritating to eyes, respiratory system and skin.
Safety Statements about 1,2-Dimethyl-3-hydroxypyrid-4-one (30652-11-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 Wear suitable gloves and eye/face protection.
Attentions:
1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
guinea pig |
LDLo |
oral |
1gm/kg (1000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FOOD INTAKE (ANIMAL)
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH |
BioMetals. Vol. 10, Pg. 247, 1997. |
mammal (species unspecified) |
LD50 |
unreported |
> 1gm/kg (1000mg/kg) |
|
Archives of Toxicology, Supplement. Vol. 18, Pg. 202, 1996. |
mouse |
LD50 |
intraperitoneal |
983mg/kg (983mg/kg) |
|
Blood. Vol. 76, Pg. 2389, 1990. |
rat |
LD50 |
intraperitoneal |
600mg/kg (600mg/kg) |
|
Drugs of the Future. Vol. 13, Pg. 413, 1988. |
rat |
LD50 |
oral |
2gm/kg (2000mg/kg) |
CARDIAC: OTHER CHANGES |
Archives of Toxicology, Supplement. Vol. 18, Pg. 202, 1996.
|