Doxifluridine cas no:3094-09-5
Synonyms: 5-Fluoro-5'-deoxyuridine;5-Fluorodesoxyuridine;5'-DFUR;5'-Deoxy-5-fluorouridine;5'-dFUrd;Flutron;Furtulon;Ro 21-9738;Uridine,5'-deoxy-5-fluoro-;Doxyflruidine;
NameDoxifluridine
CAS3094-09-5
Synonyms5-Fluoro-5'-deoxyuridine;5-Fluorodesoxyuridine;5'-DFUR;5'-Deoxy-5-fluorouridine;5'-dFUrd;Flutron;Furtulon;Ro 21-9738;Uridine,5'-deoxy-5-fluoro-;Doxyflruidine;
EINECS(EC#)221-440-1
Molecular FormulaC9H11FN2O5
Molecular Weight246.19
AppearanceWhite Solid
refractive index20 ° (C=1, H2O)
storage tempKeep tightly closed.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT, IRRITANT-HARMFUL
Hazard Xi: Irritant;
Risk R36/37/38
Safety
Hazard Codes:
Xi??
WGK Germany?:2?
RTECS:YU7526000?
Hazard Note:Irritant?
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
HazardClass: IRRITANT, IRRITANT-HARMFUL
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intravenous |
> 1gm/kg (1000mg/kg) |
? |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13(Suppl, |
| mouse |
LD50 |
subcutaneous |
> 2gm/kg (2000mg/kg) |
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13(Suppl, |
| mouse |
LDLo |
oral |
5gm/kg (5000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13(Suppl, |
| rat |
LD50 |
intravenous |
> 1gm/kg (1000mg/kg) |
? |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13(Suppl, |
| rat |
LD50 |
oral |
3390mg/kg (3390mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13(Suppl, |
| rat |
LD50 |
subcutaneous |
> 2gm/kg (2000mg/kg) |
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13(Suppl, |
