Flubendazole cas no:31430-15-6

NameFlubendazole
CAS31430-15-6
SynonymsN-{5-[(4-Fluorophenyl)carbonyl]benzimidazol-2-yl}methyloxymethanamide;Flubendazolum [INN-Latin];Flumoxane;Fluvermal;Flubenol;Flumoxal;R 17899;methyl N-[5-(4-fluorobenzoyl)-3H-benzoimidazol-2-yl]carbamate;Methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate;Carbamic acid,[5-(4-fluorobenzoyl)-1Hbenzimidazol- 2-yl]-,methyl ester;2-Benzimidazolecarbamic acid, 5- (p-fluorobenzoyl)-, methyl ester;
EINECS(EC#)250-624-4
Molecular FormulaC₁₆H₁₂FN₃O₃
Molecular Weight313.283183

Appearancewhite to pale yellow powder
refractive index1.685

Hazard UN NO.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DD6497500

CHEMICAL NAME :

2-Benzimidazolecarbamic acid, 5-(p-fluorobenzoyl)-, methyl ester

CAS REGISTRY NUMBER :

31430-15-6

LAST UPDATED :

199410

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

C16-H12-F-N3-O3

MOLECULAR WEIGHT :

313.31

WISWESSER LINE NOTATION :

T56 BM DNJ CMVO1 GVR DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2560 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>2560 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

2560 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

>2560 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

320 mg/kg

SEX/DURATION :

female 8-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

1280 mg/kg

SEX/DURATION :

female 8-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - gastrointestinal system

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

DOSE/DURATION :

100 mg/kg

REFERENCE :

PCBRD2 Progress in Clinical and Biological Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1975- Volume(issue)/page/year: 340E,225,1990