Benzeneacetic acid,3-chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)-a-methyl- cas no:31793-07-4

NameBenzeneacetic acid,3-chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)-a-methyl-
CAS31793-07-4
SynonymsHydratropicacid, 3-chloro-4-(3-pyrrolin-1-yl)- (8CI); (?à)-Pirprofen; 2-[3-Chloro-4-(2,5-dihydropyrrol-1-yl)-phenyl]propanoicacid; 2-[3-Chloro-4-(3-pyrrolin-1-yl)phenyl]propionic acid;3-Chloro-4-(3-pyrrolin-1-yl)hydratropic acid; Pirprofen; Racemic pirprofen;Rangasil 400; Rengasil; Seflenyl; Su 21524
EINECS(EC#)250-805-8
Molecular FormulaC13H14 Cl N O2
Molecular Weight251.73

refractive index1.604

Safety

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of Cl⁻ and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	193mg/kg (193mg/kg)		Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984.
hamster	LD50	oral	1190mg/kg (1190mg/kg)		Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984.
mouse	LD50	intraperitoneal	1300mg/kg (1300mg/kg)		Russian Pharmacology and Toxicology Vol. 49, Pg. 98, 1986.
mouse	LD50	oral	1350mg/kg (1350mg/kg)		Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984.
rat	LD50	intravenous	167mg/kg (167mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE	Current Therapeutic Research, Clinical & Experimental. Vol. 30(Suppl,
rat	LD50	oral	351mg/kg (351mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE	Current Therapeutic Research, Clinical & Experimental. Vol. 30(Suppl,
women	LDLo	oral	864mg/kg/54D- (864mg/kg)	BEHAVIORAL: COMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"	Netherlands Journal of Medicine. Vol. 37, Pg. 32, 1990.
women	LDLo	oral	3488mg/kg/31W (3488mg/kg)	LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"	Gastroenterology. Vol. 89, Pg. 210, 1985.
women	TDLo	oral	4624mg/kg/41W (4624mg/kg)	LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"	Gastroenterology. Vol. 89, Pg. 210, 1985.