3200-06-4|Nafronyl oxalateProducts Supply - Chemical intermediates Network

Nafronyl oxalate cas no:3200-06-4

Synonyms: Naftidrofuryl oxalate; alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate

Identification

NameNafronyl oxalate
CAS3200-06-4
SynonymsNaftidrofuryl oxalate; alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate
EINECS(EC#)221-703-0
Molecular FormulaC₂₄H₃₃NO₃^.C₂H₂O₄
Molecular Weight473.62

Safety Data

Hazard Xi: Irritant;
Risk R22
Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.
Safety Information of Nafronyl oxalate (CAS NO.3200-06-4):
Hazard Codes: Xn Harmful ,Xi Irritant
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 36
36: Wear suitable protective clothing .

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	71mg/kg (71mg/kg)		Chimica Therapeutica. Vol. 3, Pg. 463, 1968.
mouse	LD50	intramuscular	696mg/kg (696mg/kg)		Chimica Therapeutica. Vol. 3, Pg. 463, 1968.
mouse	LD50	intraperitoneal	159mg/kg (159mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 1237, 1986.
mouse	LD50	intravenous	18400ug/kg (18.4mg/kg)		United States Patent Document. Vol. #4439442,
mouse	LD50	oral	365mg/kg (365mg/kg)		United States Patent Document. Vol. #4652583,
mouse	LD50	subcutaneous	547mg/kg (547mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 1237, 1986.
rabbit	LDLo	intravenous	8mg/kg (8mg/kg)	AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 103, 1985.
rabbit	LDLo	oral	1gm/kg (1000mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 81, 1985.
rat	LD50	intraperitoneal	98mg/kg (98mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 1237, 1986.
rat	LD50	intravenous	11080ug/kg (11.08mg/kg)		United States Patent Document. Vol. #4439442,
rat	LD50	oral	711mg/kg (711mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 1237, 1986.
rat	LD50	subcutaneous	896mg/kg (896mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 1237, 1986.

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Andexin industrial Co.,Limited: Tel:86-411-39074598; Address: No.98,Shengli road,,Jinzhou district,

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Ethachem: Tel:+91 22 563 32426; Address: 101, Marine Chambers, 11 New Marine Lines Mumbai - 400 020, India

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Beijing Golden Olive Company: Tel:+86-10-8290 4532; Address: Yufu Garden No. E-4-103, Haidian District, Beijing City

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Zhejiang Haiqiang Chemical Co.,Ltd.: Tel:86-571-86960370; Address: 5/F, Around Town North Road,No. 10, Hangzhou, Zhejiang,China

Nafronyl oxalate cas no:3200-06-4

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