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Phosphoric acid,bis(2-chloroethyl) 3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester cas no:321-55-1

Synonyms: Coumarin,3-chloro-7-hydroxy-4-methyl-, bis(2-chloroethyl) phosphate (7CI,8CI);3-Chloro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one bis(chloroethyl) phosphate;3-Chloro-7-hydroxy-4-methylcoumarin bis(2-chloroethyl) phosphate; 96H60;Di-(2-chloroethyl) 3-chloro-4-methylcoumarin-7-ylphosphate; Eustidil; Galloxon;Galoxane; Galoxone; Haloxon; Helmirane; Helmiron; Helmirone; Loxon; Luxon;O,O-(2-Chloroethyl) O-(3-chloro-4-methylcoumarin-7-yl) phosphate;O,O-Bis(2-chloroethyl) O-(3-chloro-4-methyl-7-coumarinyl) phosphate; O,O-Bis(b-chloroethyl)O-(3-chloro-4-methyl-7-coumarinyl) phosphate; O,O-Di(2-chloroethyl)O-(3-chloro-4-methylcoumarin-7-yl) phosphate;O-(3-Chloro-4-methylcoumarin-7-yl) O,O-bis(2-chloroethyl) phosphate

Identification
NamePhosphoric acid,bis(2-chloroethyl) 3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
CAS321-55-1
SynonymsCoumarin,3-chloro-7-hydroxy-4-methyl-, bis(2-chloroethyl) phosphate (7CI,8CI);3-Chloro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one bis(chloroethyl) phosphate;3-Chloro-7-hydroxy-4-methylcoumarin bis(2-chloroethyl) phosphate; 96H60;Di-(2-chloroethyl) 3-chloro-4-methylcoumarin-7-ylphosphate; Eustidil; Galloxon;Galoxane; Galoxone; Haloxon; Helmirane; Helmiron; Helmirone; Loxon; Luxon;O,O-(2-Chloroethyl) O-(3-chloro-4-methylcoumarin-7-yl) phosphate;O,O-Bis(2-chloroethyl) O-(3-chloro-4-methyl-7-coumarinyl) phosphate; O,O-Bis(b-chloroethyl)O-(3-chloro-4-methyl-7-coumarinyl) phosphate; O,O-Di(2-chloroethyl)O-(3-chloro-4-methylcoumarin-7-yl) phosphate;O-(3-Chloro-4-methylcoumarin-7-yl) O,O-bis(2-chloroethyl) phosphate
EINECS(EC#)206-289-1
Molecular FormulaC14H14 Cl3 O6 P
Molecular Weight415.60
Chemical Properties
refractive index1.561
Safety Data

Safety

Moderately toxic by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of POx and Cl. See also COUMARIN; COUMARIN, 3-CHLORO-7-HYDROXY-4-METHYL-, BIS(3-CHLOROPROPYL) PHOSPHATE.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intraperitoneal 800mg/kg (800mg/kg)   Biochemical Pharmacology. Vol. 16, Pg. 1183, 1967.
chicken LD50 oral > 7gm/kg (7000mg/kg)   Biochemical Pharmacology. Vol. 16, Pg. 1183, 1967.
domestic animals - goat/sheep LD50 oral 763mg/kg (763mg/kg) behavioral: somnolence (general depressed activity) behavioral: food intake (animal) gastrointestinal: "hypermotility, diarrhea" American Journal of Veterinary Research. Vol. 41, Pg. 1857, 1980.
rabbit LD50 skin > 6gm/kg (6000mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LD50 oral 900mg/kg (900mg/kg)   Fortschritte der Arzneimittelforschung. Progress in Drug Research. Vol. 17, Pg. 108, 1973.

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