Thiirane,2-(chloromethyl)- cas no:3221-15-6

NameThiirane,2-(chloromethyl)-
CAS3221-15-6
SynonymsPropane,1-chloro-2,3-epithio- (6CI,7CI,8CI); Thiirane, (chloromethyl)- (9CI);(Chloromethyl)thiirane; 1-Chloro-2,3-epithiopropane; 2-(Chloromethyl)thiirane;2-Thiiranylmethyl chloride; 3-Chloro-1,2-propylene sulfide; 3-Chloropropenesulfide; 3-Chloropropylene sulfide; Epithiochlorohydrin; NSC 36644;Thioepichlorohydrin
Molecular FormulaC3H5 Cl S
Molecular Weight108.59

refractive index1.524-1.528
storage temp0-6°C

Hazard T: Toxic;
Risk 43-34-23/24/25
Safety Hazard Codes TRisk Statements 43-34-23/24/25Safety Statements 45-38-36/37/39-28A-26-24

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TX4725000

CHEMICAL NAME :

Propane, 1-chloro-2,3-epithio-

CAS REGISTRY NUMBER :

3221-15-6

BEILSTEIN REFERENCE NO. :

0102466

LAST UPDATED :

199612

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C3-H5-Cl-S

MOLECULAR WEIGHT :

108.59

WISWESSER LINE NOTATION :

T3STJ B1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

40 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1088,1986

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

305 ppm/6H

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Lungs, Thorax, or Respiration - acute pulmonary edema

REFERENCE :

BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 6,509,1971

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

41 mg/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 25,560,1964