1A,25-dihydroxycholecalciferol cas no:32222-06-3
Synonyms: Vitamin D3, 1a,25-Dihydroxy-; 1alpha,25-Dihydroxyvitamin D3; 1a,25-Dihydroxyvitamin; 1alpha,25-dihydroxycholecalciferol; (5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-dihydroxycholecalciferol; Calcitriol; 1,25-dihydroxyvitamin D3
Name1A,25-dihydroxycholecalciferol
CAS32222-06-3
SynonymsVitamin D3, 1a,25-Dihydroxy-; 1alpha,25-Dihydroxyvitamin D3; 1a,25-Dihydroxyvitamin; 1alpha,25-dihydroxycholecalciferol; (5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-dihydroxycholecalciferol; Calcitriol; 1,25-dihydroxyvitamin D3
EINECS(EC#)250-963-8
Molecular FormulaC27H44O3
Molecular Weight416.64
AppearanceWhite Crystalline Powder
refractive index1.547
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard T+:Verytoxic;
Risk R26/27/28;R63
Safety
A deadly poison by ingestion, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Mutation data reported. Enhances intestinal calcium transport and bone mineral mobilization. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:?
T+,
Xn
Risk Statements: 26/27/28-63-36/37/38-20/21/22
R26/27/28:Very toxic by inhalation, in contact with skin and if swallowed.?
R63:Possible risk of harm to the unborn child.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36/37/39-45-36-26
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: FZ4645000
F: 8-10-19
HazardClass: 6.1(a)
PackingGroup: I
| 1. |
??? |
dns-mus:fbr 2?μg/L
|
??? |
CNREA8 ?? Cancer Research. 46 (1986),604. |
| 2. |
??? |
scu-rat LD50:66?μg/kg
|
??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 11 (1983),4175. |
| 3. |
??? |
orl-mus LD50:1350?μg/kg
|
??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 11 (1983),4175. |
| 4. |
??? |
ipr-mus LD50:1900?μg/kg
|
??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 11 (1983),4175. |
| 5. |
??? |
scu-mus LD50:145?μg/kg
|
??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 11 (1983),4175. |
