3223-07-2|L-Phenylalanine,4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)Products Supply

L-Phenylalanine,4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1) cas no:3223-07-2

Synonyms: Alanine,3-[p-[bis(2-chloroethyl)amino]phenyl]-, monohydrochloride, L- (8CI); L-Phenylalanine,4-[bis(2-chloroethyl)amino]-, monohydrochloride (9CI); Melphalan hydrochloride

Identification

NameL-Phenylalanine,4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
CAS3223-07-2
SynonymsAlanine,3-[p-[bis(2-chloroethyl)amino]phenyl]-, monohydrochloride, L- (8CI); L-Phenylalanine,4-[bis(2-chloroethyl)amino]-, monohydrochloride (9CI); Melphalan hydrochloride
EINECS(EC#)205-726-3
Molecular FormulaC13H18 Cl2 N2 O2 . Cl H
Molecular Weight341.66

Safety Data

Safety

Deadly poison by intravenous route. Human systemic effects by ingestion: nausea and vomiting. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of Cl⁻, NO_x, and HCl.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	430ug/kg (0.43mg/kg)	BLOOD: LEUKOPENIA BLOOD: THROMBOCYTOPENIA BLOOD: OTHER CHANGES	Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965.
dog	LDLo	oral	4mg/kg (4mg/kg)	BLOOD: AGRANULOCYTOSIS BLOOD: CHANGES IN BONE MARROW NOT INCLUDED ABOVE	National Technical Information Service. Vol. PB229-000,
human	TDLo	oral	1200ug/kg/5D- (1.2mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Cancer Chemotherapy Reports, Part 1. Vol. 57, Pg. 369, 1973.
monkey	LDLo	intravenous	430ug/kg (0.43mg/kg)	BLOOD: LEUKOPENIA BLOOD: AGRANULOCYTOSIS BLOOD: OTHER CHANGES	Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965.
mouse	LD50	intravenous	23mg/kg (23mg/kg)		National Technical Information Service. Vol. PB84-162486,

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Shanghai Meicheng Chemical Co., Ltd.: Tel:86-21-50677091; Address: Room 302, Building 7, No.1000, Jinhai Road, Shanghai, 201206, China

Andexin industrial Co.,Limited: Tel:86-411-39074598; Address: No.98,Shengli road,,Jinzhou district,

L-Phenylalanine,4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1) cas no:3223-07-2

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