32385-11-8|D-Streptamine,O-3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1®6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1®4)]-2-deoxy-Products Supply

D-Streptamine,O-3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1®6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1®4)]-2-deoxy- cas no:32385-11-8

Synonyms: Sisomicin(8CI); Antibiotic 66-40; Antibiotic 6640; Rickamicin; Sch 13475; Siseptin

Identification

NameD-Streptamine,O-3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1®6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1®4)]-2-deoxy-
CAS32385-11-8
SynonymsSisomicin(8CI); Antibiotic 66-40; Antibiotic 6640; Rickamicin; Sch 13475; Siseptin
EINECS(EC#)251-018-2
Molecular FormulaC19H37N5O7
Molecular Weight447.53

Safety Data

Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	221mg/kg (221mg/kg)		"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 1, Pg. 178, 1980.
mouse	LD50	intravenous	34mg/kg (34mg/kg)		"Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977Vol. -, Pg. 239, 1977.
mouse	LD50	oral	> 5gm/kg (5000mg/kg)	SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 4, Pg. 107, 1978.
mouse	LD50	subcutaneous	177mg/kg (177mg/kg)		Chemotherapy Vol. 26(Suppl,
rat	LD50	intravenous	32mg/kg (32mg/kg)		Archives of Toxicology. Vol. 54, Pg. 275, 1983.
rat	LD50	oral	> 5gm/kg (5000mg/kg)	SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 4, Pg. 107, 1978.

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D-Streptamine,O-3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1®6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1®4)]-2-deoxy- cas no:32385-11-8

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