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DL-Adrenalin cas no:329-65-7

Synonyms: 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol; 3,4-Dihydroxy-1-[1-hydroxy-2-(methylamino)-ethyl]benzene; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; DL-Epinephrine; DL-Adrenaline

Identification
NameDL-Adrenalin
CAS329-65-7
Synonyms1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol; 3,4-Dihydroxy-1-[1-hydroxy-2-(methylamino)-ethyl]benzene; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; DL-Epinephrine; DL-Adrenaline
EINECS(EC#)206-347-6
Molecular FormulaC9H13NO3
Molecular Weight183.21
Chemical Properties
Appearanceodorless light brown or nearly white crystals
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T:Toxic;
Risk R24;R36/37/38
Safety

Safty information about DL-Adrenalin (CAS NO.329-65-7) is:

Hazard Codes: ToxicT
Risk Statements: 24-36/37/38 
R24:Toxic in contact with skin. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37-45 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: DO2975000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 7800ug/kg (7.8mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 68, Pg. 501, 1948.
mouse LD50 intravenous 3400ug/kg (3.4mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

KIDNEY, URETER, AND BLADDER: "INFLAMMATION, NECROSIS, OR SCARRING OF BLADDER"

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 502, 1949.
mouse LDLo subcutaneous 12mg/kg (12mg/kg)   "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 57, 1948.
rabbit LDLo intravenous 250ug/kg (0.25mg/kg)   "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 57, 1948.
rat LD50 intravenous 70ug/kg (0.07mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 502, 1949.

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