Glycine,3-amino-N-[(3S)-3,6-diamino-1-oxohexyl]-L-alanyl-L-seryl-L-seryl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-2-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-,(5®13)-lactam, (2S)- cas no:32988-50-4

Synonyms: Viomycin(8CI,9CI); 1,4,7,10,13-Pentaazacyclohexadecane, cyclic peptide deriv.;Celiomycin; Florimycin; Stereoisomer of3,6-diamino-N-[6-[[(aminocarbonyl)amino]methylene]-3-(2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadec-15-yl]hexanamide;Tuberactinomycin B; Vinacetin A; Vioactane

Identification

NameGlycine,3-amino-N-[(3S)-3,6-diamino-1-oxohexyl]-L-alanyl-L-seryl-L-seryl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-2-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-,(5®13)-lactam, (2S)-
CAS32988-50-4
SynonymsViomycin(8CI,9CI); 1,4,7,10,13-Pentaazacyclohexadecane, cyclic peptide deriv.;Celiomycin; Florimycin; Stereoisomer of3,6-diamino-N-[6-[[(aminocarbonyl)amino]methylene]-3-(2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadec-15-yl]hexanamide;Tuberactinomycin B; Vinacetin A; Vioactane
EINECS(EC#)251-323-0
Molecular FormulaC25H43 N13 O10
Molecular Weight685.81

Chemical Properties

refractive index1.762

Safety Data

Safety

Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, intramuscular and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Used as an antibiotic. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	ipr-rat LD50:1075 mg/kg	85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,69.
2.	scu-rat LD50:1750 mg/kg	85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,69.
3.	ivn-rat LD50:340 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),817.
4.	ims-rat LD50:1300 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),817.
5.	orl-mus LD50:1637 mg/kg	85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,69.
6.	ipr-mus LD50:973 mg/kg	ANTBAL Antibiotiki. 8 (1963),910.
7.	scu-mus LD50:1184 mg/kg	ANTBAL Antibiotiki. 8 (1963),910.
8.	ivn-mus LD50:150 mg/kg	ANTBAL Antibiotiki. 8 (1963),910.
9.	ims-mus LD50:840 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),817.

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