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2-Thiopheneacetic acid,5-benzoyl-a-methyl- cas no:33005-95-7

Synonyms: (RS)-Tiaprofenicacid;(?à)-Tiaprofenic acid;FC 3001;RU15060;Suralgan;Surgam;Tiaprofen;Tiaprofenic acid;a-(5-Benzoyl-2-thienyl)propionicacid;

Identification
Name2-Thiopheneacetic acid,5-benzoyl-a-methyl-
CAS33005-95-7
Synonyms(RS)-Tiaprofenicacid;(?à)-Tiaprofenic acid;FC 3001;RU15060;Suralgan;Surgam;Tiaprofen;Tiaprofenic acid;a-(5-Benzoyl-2-thienyl)propionicacid;
EINECS(EC#)251-329-3
Molecular FormulaC14H12O3S
Molecular Weight260.32
Chemical Properties
refractive index1.612
Safety Data

Safety

Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx.


Toxicity
1.    

orl-wmn TDLo:672 mg/kg/7W-I

    LANCAO    Lancet. 1 (1986),803.
2.    

orl-wmn TDLo:16 mg/kg/2D-I

    CMAJAX    Canadian Medical Association Journal. 137 (1987),1022.
3.    

orl-rat LD50:181 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),715.
4.    

ipr-rat LD50:225 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),715.
5.    

scu-rat LD50:215 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 15 (1984),688.
6.    

orl-mus LD50:690 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),715.
7.    

ipr-mus LD50:430 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),715.
8.    

scu-mus LD50:675 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 15 (1984),688.

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