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Amitraz cas no:33089-61-1

Synonyms: 1,5-Di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-diene; Methyl-bis(2,4-xylyliminomethyl)amine

Identification
NameAmitraz
CAS33089-61-1
Synonyms1,5-Di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-diene; Methyl-bis(2,4-xylyliminomethyl)amine
EINECS(EC#)251-375-4
Molecular FormulaC19H23N3
Molecular Weight293.4060
Chemical Properties
AppearanceWhite monoclinic crystals. Commercial product is a pale, amber brown liquid with an aromatic smell of xylene.
storage temp0-6°C
Safety Data

Hazard Xn:Harmful
Risk R22;R43;R48/22;R50/53
Safety

Safety Information of Amitraz (CAS NO.33089-61-1):
Hazard Codes: NDangerous,XnHarmful
Risk Statements: 22-43-48/22-50/53?
22:? Harmful if swallowed?
43:? May cause sensitization by skin contact?
48:? Danger of serious damage to health by prolonged exposure?
50:? Very Toxic to aquatic organisms
53:? May cause long-term adverse effects in the aquatic environment
Safety Statements: 22-24-36/37-60-61
22:? Do not breathe dust?
24:? Avoid contact with skin
36:? Wear suitable protective clothing??
37:? Wear suitable gloves?
60:? This material and/or its container must be disposed of as hazardous waste?
61:? Avoid release to the environment. Refer to special instructions safety data sheet?


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 100mg/kg (100mg/kg) ? Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 22, 1978.
duck LD50 oral 7gm/kg (7000mg/kg) ? Pesticide Manual. Vol. 9, Pg. 28, 1991.
guinea pig LD50 oral > 400mg/kg (400mg/kg) ? Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
man TDLo oral 3571mg/kg (3571mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: COMA

CARDIAC: PULSE RATE
Human & Experimental Toxicology. Vol. 16, Pg. 600, 1997.
mouse LD50 oral 1085mg/kg (1085mg/kg) ? Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (4), Pg. 36, 1995.
quail LD50 oral 788mg/kg (788mg/kg) ? Farm Chemicals Handbook. Vol. -, Pg. C20, 1991.
rabbit LD50 oral > 100mg/kg (100mg/kg) ? Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rabbit LD50 skin > 200mg/kg (200mg/kg) ? Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rat LC50 inhalation 65gm/m3/6H (65000mg/m3) ? Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rat LD50 intraperitoneal 800mg/kg (800mg/kg) ? Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rat LD50 oral 400mg/kg (400mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 80, 1989.
rat LD50 skin > 1600mg/kg (1600mg/kg) ? Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 22, 1978.
rat LD50 unreported 600mg/kg (600mg/kg) ? Japanese Journal of Toxicology. Vol. 2, Pg. 289, 1989.
rat LDLo intramuscular 250mg/kg (250mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Veterinary and Human Toxicology. Vol. 41, Pg. 355, 1999.
women LDLo oral 200uL/kg (0.2mL/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

CARDIAC: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
American Journal of Emergency Medicine. Vol. 6, Pg. 510, 1988.

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Advanced Technology & Industrial Co., Ltd.
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Alchemist International Ltd
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Agro-Care Chemical Industry Group Limited
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Address: 343 Zhongshan Road, Wuxi, Jiangsu 214001,

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