15-Crown-5 cas no:33100-27-5
Synonyms: 1,4,7,10,13-Pentaoxacyclopentadecane; Lead ionophore V; Crownpaleyellowliq; 15-Crown-5 = 1,4,7,10,13-Pentaoxacyclopentadecane; 15-crown-5-ether
Name15-Crown-5
CAS33100-27-5
Synonyms1,4,7,10,13-Pentaoxacyclopentadecane; Lead ionophore V; Crownpaleyellowliq; 15-Crown-5 = 1,4,7,10,13-Pentaoxacyclopentadecane; 15-crown-5-ether
EINECS(EC#)251-379-6
Molecular FormulaC10H20O5
Molecular Weight220.26
Appearancecolourless liquid
refractive index1.464-1.466
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn:Harmful
Risk R20/22;R36
Safety
Moderately toxic by ingestion, skin contact, and intraperitoneal routes. A skin and eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:
Xn,?
Xi?
Risk Statements: 22-36/38-36-20/22-36/37/38-20/21/22?
R22: Harmful if swallowed.?
R36/38: Irritating to eyes and skin.?
R36: Irritating to eyes.?
R20/22: Harmful by inhalation and if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-39-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S39: Wear eye / face protection.?
S36: Wear suitable protective clothing.
RIDADR: 2810
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 6.1(b)
PackingGroup of 15-Crown-5 (CAS NO.33100-27-5): III
HS Code 29329995
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
514mg/kg (514mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
| mouse |
LD50 |
oral |
1020mg/kg (1020mg/kg) |
BEHAVIORAL: TREMOR |
Toxicology and Applied Pharmacology. Vol. 44, Pg. 263, 1978. |
| rabbit |
LD50 |
intraperitoneal |
560mg/kg (560mg/kg) |
? |
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(2), Pg. 48, 1987. |
| rabbit |
LD50 |
skin |
2520mg/kg (2520mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
| rat |
LD50 |
intraperitoneal |
530mg/kg (530mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
| rat |
LD50 |
oral |
1410mg/kg (1410mg/kg) |
BEHAVIORAL: TREMOR |
Drug and Chemical Toxicology. Vol. 1, Pg. 339, 1978. |
