Bufa-4,20,22-trienolide,3-[(6-deoxy-4-O-methyl-a-L-mannopyranosyl)oxy]-14-hydroxy-, (3b)- cas no:33396-37-1

NameBufa-4,20,22-trienolide,3-[(6-deoxy-4-O-methyl-a-L-mannopyranosyl)oxy]-14-hydroxy-, (3b)-
CAS33396-37-1
SynonymsBufa-4,20,22-trienolide,3b-[(6-deoxy-4-O-methyl-a-L-mannopyranosyl)oxy]-14-hydroxy-(8CI); Clift; Meproscillarin; Methyl proscillaridin; Methyl proscillaridin A;Proscillaridin 4-methyl ether
EINECS(EC#)251-493-6
Molecular FormulaC31H44 O8
Molecular Weight544.75

refractive index1.599

Safety

Poison by ingestion and intravenous routes. Experimental reproductive effects. When Meproscillarin (CAS NO.33396-37-1) is heated to decomposition, it emits acrid smoke and irritating fumes.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	137ug/kg (0.137mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 495, 1978.
guinea pig	LDLo	intravenous	678ug/kg (0.678mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 495, 1978.
mouse	LD50	intravenous	2800ug/kg (2.8mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 506, 1978.
mouse	LD50	oral	12500ug/kg (12.5mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 506, 1978.
rat	LD50	intravenous	5800ug/kg (5.8mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 506, 1978.
rat	LD50	oral	79mg/kg (79mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 506, 1978.