3383-96-8|TemephosProducts Supply - Chemical intermediates Network

Temephos cas no:3383-96-8

Synonyms: Phosphorothioicacid, O,O-dimethyl ester, O,O-diester with 4,4'-thiodiphenol (7CI);Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester(9CI);Phosphorothioic acid, O,O'-(thiodi-p-phenylene) O,O,O',O'-tetramethylester (8CI);AC 52160;Abate;Abathion;Azai-SS;Biothion;Biothon;Difenphos;Difos;Diphos;Diphos (pesticide);EI 52160;ENT 27165;Ecopro 1707;Experimental Insecticide 52,160;Lavifos;Mosq;Nephis;Nephis 1G;O,O,O',O'-Tetramethyl O,O'-thiodi-p-phenylene phosphorothioate;Procida;Temefos;Phosphorothioic acid,Op,Op'-(thiodi-4,1-phenylene) Op,Op,Op',Op'-tetramethyl ester;

Identification

NameTemephos
CAS3383-96-8
SynonymsPhosphorothioicacid, O,O-dimethyl ester, O,O-diester with 4,4'-thiodiphenol (7CI);Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester(9CI);Phosphorothioic acid, O,O'-(thiodi-p-phenylene) O,O,O',O'-tetramethylester (8CI);AC 52160;Abate;Abathion;Azai-SS;Biothion;Biothon;Difenphos;Difos;Diphos;Diphos (pesticide);EI 52160;ENT 27165;Ecopro 1707;Experimental Insecticide 52,160;Lavifos;Mosq;Nephis;Nephis 1G;O,O,O',O'-Tetramethyl O,O'-thiodi-p-phenylene phosphorothioate;Procida;Temefos;Phosphorothioic acid,Op,Op'-(thiodi-4,1-phenylene) Op,Op,Op',Op'-tetramethyl ester;
EINECS(EC#)222-191-1
Molecular FormulaC₁₆H₂₀O₆P₂S₃
Molecular Weight466.48

Chemical Properties

AppearanceWhite crystalline solid or liquid.
refractive index1.612
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard Xi: Irritant;N: Dangerous for the environment;
Risk R21/22
Safety

Hazard Codes: Harmful Xn, Dangerous N
Risk Statements: 21/22-51/53
R21/22:Harmful in contact with skin and if swallowed.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 22-37-61-60
S22:Do not breathe dust.
S37:Wear suitable gloves.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S60:This material and its container must be disposed of as hazardous waste.
RIDADR: UN 3077
RTECS: TF6890000
Poison by ingestion. Moderately toxic by intraperitoneal, subcutaneous, and skin contact routes. An experimental teratogen. A skin irritant. A cholinesterase inhibitor type of insecticide. When heated to decomposition it emits toxic fumes of POx and SOx. See also Parathion.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	32mg/kg (32mg/kg)		Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971.
chicken	LD	subcutaneous	> 1gm/kg (1000mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	Archives of Environmental Health. Vol. 14, Pg. 283, 1967.
duck	LD50	oral	79mg/kg (79mg/kg)		Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971.
mammal (species unspecified)	LD50	oral	4700mg/kg (4700mg/kg)		Journal of the American Veterinary Medical Association. Vol. 152, Pg. 282, 1968.
mammal (species unspecified)	LD50	unreported	4gm/kg (4000mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 338, 1971.
mouse	LD50	intraperitoneal	683mg/kg (683mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 16, Pg. 297, 1969.
mouse	LD50	oral	223mg/kg (223mg/kg)		Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 1, 1966.
pigeon	LD50	oral	50mg/kg (50mg/kg)		Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971.
quail	LD50	oral	75mg/kg (75mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit	LD50	oral	313mg/kg (313mg/kg)		Veterinariya. Veterinary Science. Vol. 60(11), Pg. 63, 1984.
rabbit	LD50	skin	970mg/kg (970mg/kg)		Toxicological Information on Cyanamid Insecticides. Vol. 8/1966,
rat	LD50	intraperitoneal	912mg/kg (912mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 16, Pg. 297, 1969.
rat	LD50	oral	1gm/kg (1000mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 493, 1973.
rat	LD50	skin	1370mg/kg (1370mg/kg)		World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat	LD50	subcutaneous	2302mg/kg (2302mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 16, Pg. 297, 1969.
rat	LD50	unreported	8600mg/kg (8600mg/kg)		Travaux de la Societe de Pharmacie de Montpellier. Vol. 37(1), Pg. 45, 1977.

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