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Benzoic acid,3,6-dichloro-2-hydroxy- cas no:3401-80-7

Synonyms: Salicylicacid, 3,6-dichloro- (6CI,7CI,8CI);2-Hydroxy-3,6-dichlorobenzoic acid;3,6-DCSA;3,6-Dichloro-2-hydroxybenzoic acid;3,6-Dichlorosalicylic acid;2-hydroxy-3,6-dichlorobenzoic acid;3,6-dichloro-2-hydroxybenzoic acid;benzoic acid, 3,6-dichloro-2-hydroxy-;Dicamba metabolite;

Identification
NameBenzoic acid,3,6-dichloro-2-hydroxy-
CAS3401-80-7
SynonymsSalicylicacid, 3,6-dichloro- (6CI,7CI,8CI);2-Hydroxy-3,6-dichlorobenzoic acid;3,6-DCSA;3,6-Dichloro-2-hydroxybenzoic acid;3,6-Dichlorosalicylic acid;2-hydroxy-3,6-dichlorobenzoic acid;3,6-dichloro-2-hydroxybenzoic acid;benzoic acid, 3,6-dichloro-2-hydroxy-;Dicamba metabolite;
EINECS(EC#)222-275-8
Molecular FormulaC7H4Cl2O3
Molecular Weight207.01
Chemical Properties
refractive index1.641
Safety Data

Safety A poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of Cl−.

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO2500000
CHEMICAL NAME :
Salicylic acid, 3,6-dichloro-
CAS REGISTRY NUMBER :
3401-80-7
BEILSTEIN REFERENCE NO. :
2938787
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C7-H4-Cl2-O3
MOLECULAR WEIGHT :
207.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1560 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(10),95,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(10),95,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB85-143766
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(9),55,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
546 mg/kg/26W-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(10),95,1978
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5230 ug/m3/26W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - emphysema
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(9),55,1981

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