34031-32-8|Gold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)-Products Supply

Gold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)- cas no:34031-32-8

Synonyms: Gold,(1-thio-b-D-glucopyranosato)(triethylphosphine)-,2,3,4,6-tetraacetate (8CI); Gold, (1-thio-b-D-glucopyranose2,3,4,6-tetraacetato-S)(triethylphosphine)-; b-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, goldcomplex; Aktil; Auranofin; Crisinor; Crisofin; NSC 321521; Ridaura; Ridauran;SKF 39162; SKF 39162D; [(Tetra-O-acetyl-b-D-glucopyranosyl)thio](triethylphosphine)gold

Identification

NameGold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)-
CAS34031-32-8
SynonymsGold,(1-thio-b-D-glucopyranosato)(triethylphosphine)-,2,3,4,6-tetraacetate (8CI); Gold, (1-thio-b-D-glucopyranose2,3,4,6-tetraacetato-S)(triethylphosphine)-; b-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, goldcomplex; Aktil; Auranofin; Crisinor; Crisofin; NSC 321521; Ridaura; Ridauran;SKF 39162; SKF 39162D; [(Tetra-O-acetyl-b-D-glucopyranosyl)thio](triethylphosphine)gold
EINECS(EC#)251-801-9
Molecular FormulaC20H34 Au O9 P S
Molecular Weight678.48

Chemical Properties

AppearanceNeedles.

Safety Data

Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: ulceration or bleeding from stomach. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SO_x and PO_x. See also GOLD COMPOUNDS.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	3200ug/kg (3.2mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
man	TDLo	oral	1200ug/kg/2W- (1.2mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Journal of Rheumatology. Vol. 13, Pg. 228, 1986.
mouse	LD50	intraperitoneal	33800ug/kg (33.8mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
mouse	LD50	intravenous	22600ug/kg (22.6mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
mouse	LD50	oral	84940ug/kg (84.94mg/kg)		Bollettino Chimico Farmaceutico. Vol. 128, Pg. 22, 1989.
mouse	LD50	subcutaneous	53600ug/kg (53.6mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	intraperitoneal	25500ug/kg (25.5mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	intravenous	39mg/kg (39mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	oral	265mg/kg (265mg/kg)		Veterinary Pathology. Vol. 15(Suppl,
rat	LD50	subcutaneous	235mg/kg (235mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
women	TDLo	oral	5400ug/kg/10D (5.4mg/kg)	BEHAVIORAL: TOXIC PSYCHOSIS BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Arthritis and Rheumatism. Vol. 27, Pg. 1316, 1984.

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Gold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)- cas no:34031-32-8

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