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Safety
The Safety Statements of Methylthioinosine (CAS NO.342-69-8):
S22:Do not breathe dust. S24/25:Avoid contact with skin and eyes.
Poison by intraperitoneal route. Experimental teratogenic effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
The toxicity of Methylthioinosine (CAS NO.342-69-8):
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD10 | unreported | 20mg/kg (20mg/kg) | Progress in Medical Chemistry. Vol. 7, Pg. 69, 1970. | |
mouse | LD50 | intraperitoneal | 137mg/kg (137mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
rat | LD50 | intraperitoneal | 65mg/kg (65mg/kg) | Archives of Pathology. Vol. 86, Pg. 395, 1968. |
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