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DL-1,4-Dithiothreitol cas no:3483-12-3

Synonyms: 2,3-Butanediol,1,4-dimercapto-, (R*,R*)-;Threitol, 1,4-dithio- (7CI,8CI);1,4-Dithio-DL-threitol;1,4-Dithiothreitol;Cleland's reagent;DL-1,4-Dimercapto-2,3-dihydroxybutane;Dithiothreitol;DTT (threitol derivative);Reagents, Cleland's;Sputolysin;WR 34678;rac-Dithiothreitol;threo-1,4-Dimercapto-2,3-butanediol;threo-2,3-Dihydroxy-1,4-butanedithiol;threo-2,3-Dihydroxy-1,4-dithiolbutane;2,3-Butanediol,1,4-dimercapto-, (2R,3R)-rel-;

Identification
NameDL-1,4-Dithiothreitol
CAS3483-12-3
Synonyms2,3-Butanediol,1,4-dimercapto-, (R*,R*)-;Threitol, 1,4-dithio- (7CI,8CI);1,4-Dithio-DL-threitol;1,4-Dithiothreitol;Cleland's reagent;DL-1,4-Dimercapto-2,3-dihydroxybutane;Dithiothreitol;DTT (threitol derivative);Reagents, Cleland's;Sputolysin;WR 34678;rac-Dithiothreitol;threo-1,4-Dimercapto-2,3-butanediol;threo-2,3-Dihydroxy-1,4-butanedithiol;threo-2,3-Dihydroxy-1,4-dithiolbutane;2,3-Butanediol,1,4-dimercapto-, (2R,3R)-rel-;
EINECS(EC#)222-468-7
Molecular FormulaC4H10O2S2
Molecular Weight154.25
Chemical Properties
AppearanceWhite solid
storage temp2-8°C
Sensitive Air Sensitive
Safety Data

Hazard Xn:Harmful
Risk R22;R36/37/38
Safety

Hazard Codes of Dithiothreitol (CAS NO.3483-12-3):?HarmfulXn
Risk Statements: 25-36/37/38-20/21/22?
R25: Toxic if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-45-37/39-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S37/39: Wear suitable gloves and eye/face protection.?
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: EK1610000
F: 3-10-16-23
Poison by subcutaneous, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 108mg/kg (108mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacy and Pharmacology. Vol. 1, Pg. 576, 1949.
mouse LD50 intraperitoneal 154mg/kg (154mg/kg) ? Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 1419, 1974.

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