Ajmalanium,17,21-dihydroxy-4-propyl-, (17R,21a)- cas no:35080-11-6

NameAjmalanium,17,21-dihydroxy-4-propyl-, (17R,21a)-
CAS35080-11-6
Synonyms5H-6,10:11,12a-Dimethanoindolo[3,2-b]quinolizine,ajmalanium deriv.; 17R,21a-Dihydroxy-4-propylajmalanium; N-Propylajmaline; N-Propylajmalinium;N4-Propylajalmalinium; N4-Propylajmalinium; Prajmaline; Prajmalium
Molecular FormulaC23H33 N2 O2
Molecular Weight369.58

Safety

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x. See also other ajmalines.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	3400ug/kg (3.4mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Chemical and Pharmaceutical Bulletin. Vol. 22, Pg. 2329, 1974.
mouse	LD50	oral	65500ug/kg (65.5mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Chemical and Pharmaceutical Bulletin. Vol. 22, Pg. 2329, 1974.
rat	LD50	intravenous	1400ug/kg (1.4mg/kg)	CARDIAC: OTHER CHANGES	Pharmazie. Vol. 31, Pg. 36, 1976.