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Bendamustine hydrochloride cas no:3543-75-7

Synonyms: 1H-Benzimidazole-2-butanoicacid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride (9CI);2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl-,monohydrochloride (8CI);1H-Benzimidazole-2-butanoicacid, 5-[bis(2-chloroethyl)amino]-1-methyl-, hydrochloride (1:1);Cytostasan;IMET 3393;Ribomustin;SDX 105;ZIMET 33/93;Bendamustine HCl;

Identification
NameBendamustine hydrochloride
CAS3543-75-7
Synonyms1H-Benzimidazole-2-butanoicacid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride (9CI);2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl-,monohydrochloride (8CI);1H-Benzimidazole-2-butanoicacid, 5-[bis(2-chloroethyl)amino]-1-methyl-, hydrochloride (1:1);Cytostasan;IMET 3393;Ribomustin;SDX 105;ZIMET 33/93;Bendamustine HCl;
Molecular FormulaC16H22Cl3N3O2
Molecular Weight394.76
Chemical Properties
Appearancepale brown crystals
Safety Data

Safety

A poison by ingestion, intravenous, and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic and teratogenic data. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NOx.


Toxicity
1. ???

orl-mus TDLo:250?mg/kg/4D-I:CAR

??? ARGEAR ?? Archiv fuer Geschwulstforschung. 43 (1974),16.
2. ???

ipr-mus TDLo:50?mg/kg/4D-I:CAR

??? ARGEAR ?? Archiv fuer Geschwulstforschung. 43 (1974),16.
3. ???

orl-rat LD50:200?mg/kg

??? ATSUDG ?? Archives of Toxicology, Supplement. 8 (1985),504.
4. ???

ivn-rat LD50:40?mg/kg

??? ATSUDG ?? Archives of Toxicology, Supplement. 8 (1985),504.
5. ???

orl-mus LD50:250?mg/kg

??? ARGEAR ?? Archiv fuer Geschwulstforschung. 43 (1974),16.
6. ???

ipr-mus LD50:100?mg/kg

??? ARGEAR ?? Archiv fuer Geschwulstforschung. 43 (1974),16.
7. ???

ivn-mus LD50:80?mg/kg

??? ATSUDG ?? Archives of Toxicology, Supplement. 8 (1985),504.

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Facus Pharmaceutical Co., Ltd.
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Hangzhou Tacon Co., Ltd.
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