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Safety
Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When Nifurthiazole (CAS NO.3570-75-0) is heated to decomposition, it emits very toxic fumes of NOx and SOx.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 445mg/kg (445mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
Antimicrobial Agents and Chemotherapy Vol. -, Pg. 268, 1962. |
| mouse | LD50 | oral | 1400mg/kg (1400mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
Antimicrobial Agents and Chemotherapy Vol. -, Pg. 268, 1962. |
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