5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[[(2R)-2-amino-2-phenylacetyl]amino]-8-oxo-,(6R,7R)- cas no:3577-01-3

Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[[(2R)-2-amino-2-phenylacetyl]amino]-8-oxo-,(6R,7R)-
CAS3577-01-3
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[(aminophenylacetyl)amino]-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-7-[[(2R)-aminophenylacetyl]amino]-8-oxo-, (6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-(2-amino-2-phenylacetamido)-3-(hydroxymethyl)-8-oxo-, acetate (ester), D-(8CI); 7-(2-D-a-Aminophenylacetamido)cephalosporanicacid; Cefaloglycin; Cefaloglycine; Cephaloglycin; Cephaloglycine;D-(-)-Cephaloglycin; D-Cephaloglycine; Kafocin; Kefglycin; Lilly 39435
EINECS(EC#)222-696-7
Molecular FormulaC18H19 N3 O6 S
Molecular Weight405.46

refractive index1.678

Safety

Moderately toxic by subcutaneous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1030mg/kg (1030mg/kg)	kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)"	Chemotherapy Vol. 18, Pg. 22, 1970.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	liver: other changes	Chemotherapy Vol. 18, Pg. 22, 1970.
mouse	LD50	subcutaneous	3700mg/kg (3700mg/kg)	kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)"	Chemotherapy Vol. 18, Pg. 22, 1970.
rat	LD50	intraperitoneal	1300mg/kg (1300mg/kg)	kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)"	Chemotherapy Vol. 18, Pg. 22, 1970.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	liver: other changes	Chemotherapy Vol. 18, Pg. 22, 1970.
rat	LD50	subcutaneous	2800mg/kg (2800mg/kg)	kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)"	Chemotherapy Vol. 18, Pg. 22, 1970.