2(3H)-Benzothiazolone,5-chloro-3-[2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl]-, hydrochloride(1:1) cas no:35941-71-0

Name2(3H)-Benzothiazolone,5-chloro-3-[2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl]-, hydrochloride(1:1)
CAS35941-71-0
Synonyms1-Piperazineethanol,4-[(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl]-, monohydrochloride (9CI); FK1160; NTA 194; RHC 2592; Solantal; Tiaramide hydrochloride
EINECS(EC#)252-802-7
Molecular FormulaC15H18 Cl N3 O3 S . Cl H
Molecular Weight392.33

Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. An eye irritant. When heated to decomposition it emits very toxic fumes of Cl⁻, NO_x, and SO_x.

1.		eye-rbt 200 mg rns MLD		ARZNAD    Arzneimittel-Forschung. Drug Research. 22 (1972),724.
2.		orl-rat LD50:2300 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 32 (1982),225.
3.		ipr-rat LD50:530 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),451.
4.		scu-rat LD50:930 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),504.
5.		ivn-rat LD50:203 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),504.
6.		orl-mus LD50:564 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),504.
7.		ipr-mus LD50:298 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),504.
8.		scu-mus LD50:375 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),504.
9.		ivn-mus LD50:178 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),504.