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Home > products > [1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,(1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)-

[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,(1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)- cas no:36011-19-5

Synonyms: 21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)-;Cytochalasin E; NSC 175151; [1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,[4S-(1E,4R*,6S*,7E,11aR*,14R*,14aR*,15R*,15aS*,16aR*,16bR*)]-

Identification
Name[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,(1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)-
CAS36011-19-5
Synonyms21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)-;Cytochalasin E; NSC 175151; [1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,[4S-(1E,4R*,6S*,7E,11aR*,14R*,14aR*,15R*,15aS*,16aR*,16bR*)]-
EINECS(EC#)252-835-7
Molecular FormulaC28H33 N O7
Molecular Weight495.56412
Chemical Properties
AppearanceWhite powder.
refractive index1.608
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T+,T
Risk R26/27/28
Safety

A poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
T: Toxic
T+: Very toxic
Risk Statements about Cytochalasin E (CAS No.:36011-19-5):
R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed. 
R63 Possible risk of harm to the unborn child.
Safety Statements about Cytochalasin E (CAS No.:36011-19-5):
S28 After contact with skin, wash immediately with plenty of soap-suds.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.


Toxicity
1.    

ipr-mus LD50:2700 µg/kg

    FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 38 (1979),438.
2.    

ipr-gpg LD50:500 µg/kg

    JJEMAG    Japanese Journal of Experimental Medicine. 48 (1978),105.

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