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Home > products > Estra-1,3,5(10)-triene-3,17-diol,2-methoxy-, (17b)-

Estra-1,3,5(10)-triene-3,17-diol,2-methoxy-, (17b)- cas no:362-07-2

Synonyms: Estra-1,3,5(10)-triene-3,17b-diol, 2-methoxy- (7CI,8CI);Estradiol, 2-methoxy- (6CI);2-Hydroxyestradiol 2-methyl ether;2-Methoxyestra-1,3,5(10)-triene-3,17b-diol;NSC 659853;Panzem;

Identification
NameEstra-1,3,5(10)-triene-3,17-diol,2-methoxy-, (17b)-
CAS362-07-2
SynonymsEstra-1,3,5(10)-triene-3,17b-diol, 2-methoxy- (7CI,8CI);Estradiol, 2-methoxy- (6CI);2-Hydroxyestradiol 2-methyl ether;2-Methoxyestra-1,3,5(10)-triene-3,17b-diol;NSC 659853;Panzem;
Molecular FormulaC19H26O3
Molecular Weight302.41
Chemical Properties
AppearanceOff-white solid
refractive index1.586
storage temp−20°C
Safety Data

Hazard T: Toxic;
Risk R23/24/25
Safety

Mutation data reported. When heated to decomposition 2-Methoxyestradiol (CAS.362-07-2) emits acrid smoke and irritating vapors.
Hazard Codes: ToxicT,IrritantXi
Risk Statements: 23/24/25-36/37/38-48-61-60-46-45 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R45:May cause cancer. 
R46:May cause heritable genetic damage. 
R60:May impair fertility. 
R61:May cause harm to the unborn child.
Safety Statements: 22-26-36/37/39-45-53-36 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53:Avoid exposure - obtain special instructions before use.


Toxicity
1.    

mnt-ham-emb 300 µg/

    CRNGDP    Carcinogenesis. 21 (2000),735.
2.    

mor-ham-emb 100 µg/

    CRNGDP    Carcinogenesis. 21 (2000),735.
3.    

cyt-ham-emb 300 µg/

    CRNGDP    Carcinogenesis. 21 (2000),735.
4.    

sln-ham-emb 300 µg/

    CRNGDP    Carcinogenesis. 21 (2000),735.
5.    

msc-ham-emb 100 µg/

    CRNGDP    Carcinogenesis. 21 (2000),735.
6.    

mor-ham-emb 0.1 mg/L/48H

    CRNGDP    Carcinogenesis. 21 (2000),735.
7.    

cyt-ham-emb 0.3 mg/L/24H

    CRNGDP    Carcinogenesis. 21 (2000),735.

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