2H-1-Benzopyran-2-one,8-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-, hydrochloride(1:1) cas no:36556-75-9

Name2H-1-Benzopyran-2-one,8-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-, hydrochloride(1:1)
CAS36556-75-9
Synonyms2H-1-Benzopyran-2-one,8-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-, hydrochloride(9CI); 2H-1-Benzopyran-2-one,8-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-, hydrochloride, (?à)-; (?à)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarinhydrochloride; 8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarinhydrochloride; Bucumarol; Bucumolol hydrochloride; CS 359;DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride;dl-Bucumolol hydrochloride
Molecular FormulaC17H23 N O4 . Cl H
Molecular Weight341.87

Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. When Bucumolol hydrochloride (CAS NO.36556-75-9) is heated to decomposition, it emits toxic fumes of NO_x and HCl.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	59200ug/kg (59.2mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.
mouse	LD50	intravenous	31600ug/kg (31.6mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Japanese Journal of Pharmacology. Vol. 23, Pg. 497, 1973.
mouse	LD50	oral	676mg/kg (676mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.
mouse	LD50	subcutaneous	82300ug/kg (82.3mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.
rat	LD50	intraperitoneal	59200ug/kg (59.2mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 131, 1982.
rat	LD50	intravenous	31600ug/kg (31.6mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 131, 1982.
rat	LD50	oral	676mg/kg (676mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 131, 1982.
rat	LD50	subcutaneous	82300ug/kg (82.3mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 131, 1982.